Case studies
Explore CMAC’s case studies to see how our research and innovation in medicines manufacturing is delivering real-world impact across industry, regulation, and academia.
Featured
ESTAN is a user‑friendly modelling toolbox developed by Loughborough University in collaboration with CMAC’s Digital Manufacturing Research Centre. It simplifies complex sensitivity and estimability analyses, helping users build mathematical models and digital twins with stronger predictive performance.
Through digital-first process design, CMAC researchers decrease the material required for API development by an order of magnitude.
Researchers at Eli Lilly & Company have successfully applied CMAC’s impurity rejection workflow in clinical development, achieving up to 100% rejection of problematic impurities.
Model-based Digitalisation Framework Development for Continuous Manufacturing Processes
Workflows for the Application of a User-friendly Mechanistic Modelling Toolkit
Considerable time has been spent as part of the EPSRC CMAC CIM research campaign, designing and implementing a workflow for continuous cooling crystallisation.
This research explores possibilities to align future value network configurations and disruptive shifts in manufacturing and information technologies.
Computer Aided Process Design (CAPD) and simulation tools have been successfully implemented in the chemical and oil industries since the early 60s to accelerate development and optimise the design and operation of process.
Along with nucleation and growth, agglomeration is a commonly occurring process in crystallisation operations.
The “Make To Order Processing Plants” (MOPPs) project involving CMAC, CPI, AstraZeneca and led by Perceptive Engineering.
The particle engineering research group under the supervision of Prof Jan Sefcik has designed and investigated a novel continuous seed production unit.