Knowledge Transfer Partnerships
Model-based Digitalisation Framework Development for Continuous Manufacturing Processes
This Innovate UK Knowledge Transfer Partnership project is a collaboration between the University of Sheffield and Process Systems Enterprise (PSE, now a Siemens business). The aim of the project was to develop a systematic methodology for the application of a mechanistic-based digitalisation framework, to enable pharmaceutical and other industries to effectively and efficiently design and implement continuous manufacturing processes. The project has lead to the development of mechanistic models for continuous pharmaceutical manufacturing, successfully implemented in gPROMS Formulated Products software and validated using the continuous pharmaceutical manufacturing facilities at the University of Sheffield.
Workflows for the Application of a User-friendly Mechanistic Modelling Toolkit
This KTP project is a joint-venture between CMAC and PSE aimed at:
Creating industrial workflows for the application of a user-friendly mechanistic modelling toolkit for active ingredient manufacture
Delivering step-change improvements in functionality and usability of gPROMS Formulated Products
Developing an enhanced tool accessible to a wide range of users – from non-expert operators/users to skilled modellers/engineers
This embedded novel capability will be facilitated by an underpinning knowledge of both advanced batch and continuous pharmaceutical processes and how to integrate these to achieve robust modelling tools for end-to-end pharmaceutical manufacture.
