The DM² Accelerator focused on strengthening CMAC’s ability to translate digital research into industrially relevant manufacturing practice. Specifically, the project included: Advancement of CMAC’s cyber‑physical research infrastructure (CPRI), building on DM² Phase 1 and integrating digital, data and physical manufacturing capabilities across the CMC DataFactories®.

Development and integration of advanced digital workflows, including interoperable data structures, modelling, automation and orchestration across crystallisation, tableting and connected manufacturing processes.

Demonstration and validation through industry‑relevant case studies and trials, co‑created with pharmaceutical partners to test usability, readiness and value in realistic settings.

Creation of translation and adoption assets, such as technology transfer packages, standardised architectures, workflows and user requirements to support uptake by large pharma and SMEs.

Skills development and upskilling in digital pharmaceutical manufacturing for researchers, industry partners and the wider sector.

Support for sustainability and responsiveness in manufacturing, aligned with UK advanced manufacturing ambitions, through digital‑first, data‑enabled approaches.