ANNUAL REVIEW 2025 | 15 YEARS OF CMAC
Fifteen years of transforming how medicines are made.
From digital-first process design and self-driving DataFactories to sustainable manufacturing and advanced material insights, here's how our research, training, facilities and industry partnerships delivered in 2025.
64 pages. Published September 2026. Also available as an accessible text version.
50+
Events and visits hosted onsite in 2025
170
Staff, researchers, academics and PhD students
15
Years since CMAC was founded in 2011
£200m
Cumulative funding investment in CMAC
60
Partners across industry, academia and technology
WELCOME FROM THE DIRECTOR
“CMAC's vision, collaboration and commitment remain strong, driving innovation at scale and shaping the future of pharmaceutical manufacturing.”
Prof. Alastair Florence, Director, CMAC
EXPLORE THE REVIEW
Four pillars. One mission.
Jump straight to the chapter you need. Each link opens the PDF at the right page
01
Research Excellence and Intensity
MediForge, SolvIT, DM² Accelerator, DDMAP and our digital CMC portfolio.
Read chapter - pp. 16-37
02
Outstanding Skills Development
Our MSc, the CEDAR CDT, Living Labs and the SkillsFactory platform.
Read chapter - pp. 38-43
03
World-Class Facilities
Investment, new equipment, the Data Lab and our journey to net zero.
Read chapter - pp. 44-49
04
Translation to Industry
OpenCMC™, PhD@Work and a case study in spherical agglomeration.
Read chapter - pp. 50-57
HIGHLIGHTS FROM 2025
The stories behind the numbers
HEADLINE PROGRAMME | MEDIFORGE
Advancing an Industry 5.0 future for sustainable medicines manufacturing
In its second year, the £11m programme has shown replicable flow synthesis across Leeds and Strathclyde, secure FAIR data sharing, and early integration of crystallisation, tableting and dissolution.
RESEARCH | DM² ACCELERATOR
Scaling digital CMC for smarter, faster medicines
Six demonstration trials with partners including AstraZeneca, Shionogi and Lonza, plus a live Knowledge Graph.
6 industry demonstration trials delivered
RESEARCH | SolvIT
Designing greener solvents for API manufacture
With Imperial College London and Lilly, SolvIT combines modelling and experiments to cut solvent waste and cost.
100kg hazardous waste per 1kg of API: the problem we are tackling
FACILITIES | NET ZERO
Labs that measure and cut their own footprint
Real-time energy monitoring across 250+ assets, more efficient instruments and lab automation.
15.5 tCO₂e saved per year
Collaboration that drives progress
We co-create and co-deliver with partners across global pharma, technology providers and academia. Thank you to everyone who made 2025 possible.
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