CCDC Health Check
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This course provides an overview of the Cambridge Crystallisation Data Centre (CCDC) Health Check for assessing physical form stability. In this course, we’ll look at the steps of the CCDC health check from loading the structure to conformational analysis, interaction analysis, and hydrogen bond analysis and crystal packing assessment. For each step, links are provided for the relevant CCDC training materials.
The course also applies key regulatory science concepts including the question of interest, context of use, model risk, and the credibility assessment of computational models according to the Digital CMC Regulatory Lifecycle framework.
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An Overview of CERSI Training Courses and Course-Specific Learning Objectives
Module Introduction
Question of Interest
Context of Use
Assumptions and Limitations
Risk Assessment
The CCDC Health Check: A High-Level Overview
Getting Started with the CCDC’s Mercury Software
Assessing Conformation
Assessing Hydrogen Bonding
Assessing Aromatic Interactions
Assessing Intermolecular Interactions with Full Interaction Maps
Assessing Crystal Packing
Module Recap
Module Quiz
References
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Gain an understanding of what the CCDC Health Check is
Understand the Question of Interest, Context of Use and Risk Level associated with the CCDC Health Check
Learn where CCDC learning resources can be found for each step of the CCDC Health Check and have the opportunity to download and follow self-guided workshops from the CCDC
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Pharmaceutical professionals, regulatory affairs professionals, regulators and researchers who want to understand the concepts and methods underlying these computational models and associated predictive tools.
This course is delivered by CMAC’s Digital CMC CERSI team.
Available now
Format: E-learning
Free for CMAC and CERSI members and partners
Approx 1 hour
Register your interest:
