Dyneval partnership brings advanced nanoparticle and crystallisation insights to CMAC
CMAC has announced that Dyneval, the Edinburgh-based particle characterisation company, has joined the Centre as a Tier Two member, bringing its innovative particle sizing platform with significant potential applications across pharmaceutical formulation and process research.
The partnership reflects a wider pattern taking shape across the pharmaceutical sector as technology providers and manufacturers increasingly engage in pre-competitive, collaborative research and work directly with researchers using their technology.
Working with CMAC gives Dyneval a direct route into applied pharmaceutical research where their novel characterisation platform can integrate into innovative pre-competitive research projects. The arrangement works both ways: Dyneval extends its reach into pharmaceutical development, and CMAC’s researchers have access to new capabilities, strengthening the collaborative ecosystem at the centre of CMAC’s model.
Dyneval's flagship instrument, the Lumero® particle size analyser, introduces new capabilities and represents advancements in particle characterisation. Powered by Dyneval's proprietary VISTA (Video Intensity Spatio-Temporal Analysis) algorithm, the Lumero® delivers precise size distributions across a range spanning tens of nanometres to several microns. It can handle opaque samples with little or no dilution required and demands no prior knowledge of refractive index from the operator, lowering the barrier to high-quality, reproducible measurements.
Professor Yvonne Perrie, whose group specialises in lipid nanoparticle formulation, has already held early discussions with Dyneval about the potential of the Lumero® for nanoparticle characterisation and the value to CMAC research.
Professor Jan Sefcik, CMAC academic leader, whose group focuses on crystallisation and particle engineering, has already been working with the instrument to examine how it can support mechanistic understanding at the early stages of lipid nanoparticle formation.
“We are particularly interested in using this technology for monitoring of particle formation under flow conditions, which would be especially relevant for self-assembly and precipitation processes including nanoparticle formation and antisolvent crystallisation.”
Now installed within the CMAC facilities at the University of Strathclyde, the Lumero® fits squarely within CMAC's mission to develop and integrate innovative process analytical technologies into continuous pharmaceutical manufacturing. As a compact, benchtop system, it offers real practical advantages for both laboratory research and process development environments.
Dyneval, registered in Scotland and headquartered in Edinburgh, develops platform technologies for dynamic analysis at the nano- and microscale. Their membership strengthens CMAC's growing network of industry partners and adds a genuinely novel characterisation tool to the Centre's capabilities.
This is a clear example of what CMAC’s Tier Two offer delivers: a route for technology companies to embed their products within applied pharmaceutical research, and to test and validate their technology while accelerating innovative research programmes.
To find out more about Dyneval and Lumero®, visit www.dyneval.com.
About CMAC
CMAC is an internationally leading medicines manufacturing research centre led by the University of Strathclyde. Combining academic excellence with applied and pre-competitive research, CMAC partners with industry, academia and innovation stakeholders, including government and funding agencies, to transform medicines development, manufacture, and supply.
Our National Facility and vibrant portfolio of projects enable industry collaboration on cutting-edge research. Through advanced training and translation programmes, CMAC equips researchers and professionals with the skills to lead innovation in digital pharmaceutical manufacturing, supporting the sector’s evolution toward more resilient, sustainable and patient-focused solutions.
About Dyneval
Dyneval is a science-led measurement technology company founded by physicists from the University of Edinburgh. Combining scientific expertise with applied research and innovation, Dyneval develops automated technologies that reveal the behaviour of subvisible particles in complex samples, from biological fluids to pharmaceutical formulations.
Dyneval’s product portfolio includes Lumero®, a particle size analyser designed to measure complex and concentrated samples with little or no dilution, and Dynescan, an automated semen analyser for animal breeding. By generating reliable, actionable data, Dyneval helps researchers and industry professionals better understand product performance, accelerate development and improve manufacturing decisions.