Digital Pharmaceutical Process Design: Faster, Cost Effective and Sustainable Delivery of Quality Drug Substance
Through digital-first process design, CMAC researchers decrease the material required for API development by an order of magnitude.
From Lab to Clinical Development: CMAC’s Impurity Rejection Workflow
Researchers at Eli Lilly & Company have successfully applied CMAC’s impurity rejection workflow in clinical development, achieving up to 100% rejection of problematic impurities.
Knowledge Transfer Partnerships
Model-based Digitalisation Framework Development for Continuous Manufacturing Processes
Workflows for the Application of a User-friendly Mechanistic Modelling Toolkit
Developing Workflows for Continuous Crystallisation
Considerable time has been spent as part of the EPSRC CMAC CIM research campaign, designing and implementing a workflow for continuous cooling crystallisation.
Manufacturing Operations and Supply Chain Management Challenges in Continuous Manufacturing
This research explores possibilities to align future value network configurations and disruptive shifts in manufacturing and information technologies.
From Molecule to Lab to Plant: Computer Aided Process Design
Computer Aided Process Design (CAPD) and simulation tools have been successfully implemented in the chemical and oil industries since the early 60s to accelerate development and optimise the design and operation of process.
Exquisite Particles: Towards predicting agglomeration in APIs
Along with nucleation and growth, agglomeration is a commonly occurring process in crystallisation operations.
Made to Order Processing Plant
The “Make To Order Processing Plants” (MOPPs) project involving CMAC, CPI, AstraZeneca and led by Perceptive Engineering.
Platform Technology Development
The particle engineering research group under the supervision of Prof Jan Sefcik has designed and investigated a novel continuous seed production unit.
Improved Manufacture of a Melt-Cast Explosive
In the production of many materials solid state variation is recognised as a key issue.
Solid State Selection Using a Novel Nucleator Coupled With Design of Experiment (DoE)
In the production of many materials solid state variation is recognised as a key issue.