Publication 2015
Badman, C.; Trout, B. L., Achieving continuous manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium. J Pharm Sci 2015, 104 (3), 779-80. https://doi.org/10.1002/jps.24246
Baxendale, I. R.; Braatz, R. D.; Hodnett, B. K.; Jensen, K. F.; Johnson, M. D.; Sharratt, P.; Sherlock, J. P.; Florence, A. J., Achieving continuous manufacturing: technologies and approaches for synthesis, workup, and isolation of drug substance. May 20-21, 2014 Continuous Manufacturing Symposium. J Pharm Sci 2015, 104 (3), 781-91. https://doi.org/10.1002/jps.24252
Bhardwaj, R. M.; Johnston, A.; Johnston, B. F.; Florence, A. J., A random forest model for predicting the crystallisability of organic molecules. Crystengcomm 2015, 17 (23), 4272-4275. https://doi.org/10.1039/c4ce02403f
Bhardwaj, R. M.; Raval, V.; Oswald, I. D.; Florence, A. J., Crystal structure of a mixed solvated form of amoxapine acetate. Acta Crystallogr E Crystallogr Commun 2015, 71 (Pt 2), 139-41. https://doi.org/10.1107/S2056989014028096
Brandel, C.; ter Horst, J. H., Measuring induction times and crystal nucleation rates. Faraday Discuss 2015, 179 (0), 199-214. https://doi.org/10.1039/C4FD00230J
Briggs, N. E. B.; Schacht, U.; Raval, V.; McGlone, T.; Sefcik, J.; Florence, A. J., Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer. Organic Process Research & Development 2015, 19 (12), 1903-1911. https://doi.org/10.1021/acs.oprd.5b00206
Brown, C. J.; Adelakun, J. A.; Ni, X. W., Characterization and modelling of antisolvent crystallization of salicylic acid in a continuous oscillatory baffled crystallizer. Chem Eng Process 2015, 97, 180-186. https://doi.org/10.1016/j.cep.2015.04.012
Hendon, C. H.; Wittering, K. E.; Chen, T. H.; Kaveevivitchai, W.; Popov, I.; Butler, K. T.; Wilson, C. C.; Cruickshank, D. L.; Miljanic, O. S.; Walsh, A., Absorbate-induced piezochromism in a porous molecular crystal. Nano Lett 2015, 15 (3), 2149-54. https://doi.org/10.1021/acs.nanolett.5b00144
Hunter, S.; Coster, P. L.; Davidson, A. J.; Millar, D. I. A.; Parker, S. F.; Marshall, W. G.; Smith, R. I.; Morrison, C. A.; Pulham, C. R., High-Pressure Experimental and DFT-D Structural Studies of the Energetic Material FOX-7. J Phys Chem C 2015, 119 (5), 2322-2334. https://doi.org/10.1021/jp5110888
Jawor-Baczynska, A.; Moore, B. D.; Sefcik, J., Effect of mixing, concentration and temperature on the formation of mesostructured solutions and their role in the nucleation of DL-valine crystals. Faraday Discuss 2015, 179 (0), 141-54. https://doi.org/10.1039/C4FD00262H
McGlone, T.; Briggs, N. E. B.; Clark, C. A.; Brown, C. J.; Sefcik, J.; Florence, A. J., Oscillatory Flow Reactors (OFRs) for Continuous Manufacturing and Crystallization. Organic Process Research & Development 2015, 19 (9), 1186-1202. https://doi.org/10.1021/acs.oprd.5b00225
Powell, K. A.; Bartolini, G.; Wittering, K. E.; Saleemi, A. N.; Wilson, C. C.; Rielly, C. D.; Nagy, Z. K., Toward Continuous Crystallization of Urea-Barbituric Acid: A Polymorphic Co-Crystal System. Crystal Growth & Design 2015, 15 (10), 4821-4836. https://doi.org/10.1021/acs.cgd.5b00599
Powell, K. A.; Saleemi, A. N.; Rielly, C. D.; Nagy, Z. K., Periodic steady-state flow crystallization of a pharmaceutical drug using MSMPR operation. Chem Eng Process 2015, 97 (0), 195-212. https://doi.org/10.1016/j.cep.2015.01.002
Reus, M. A.; van der Heijden, A. E. D. M.; ter Horst, J. H., Solubility Determination from Clear Points upon Solvent Addition. Organic Process Research & Development 2015, 19 (8), 1004-1011. https://doi.org/10.1021/acs.oprd.5b00156
Sans, V.; Porwol, L.; Dragone, V.; Cronin, L., A self optimizing synthetic organic reactor system using real-time in-line NMR spectroscopy. Chem Sci 2015, 6 (2), 1258-1264. https://doi.org/10.1039/C4SC03075C
Sayin, R.; Martinez-Marcos, L.; Osorio, J. G.; Cruise, P.; Jones, I.; Halbert, G. W.; Lamprou, D. A.; Litster, J. D., Investigation of an 11mm diameter twin screw granulator: Screw element performance and in-line monitoring via image analysis. Int J Pharm 2015, 496 (1), 24-32. https://doi.org/10.1016/j.ijpharm.2015.09.024
Siddique, H.; Brown, C. J.; Houson, I.; Florence, A. J., Establishment of a Continuous Sonocrystallization Process for Lactose in an Oscillatory Baffled Crystallizer. Organic Process Research & Development 2015, 19 (12), 1871-1881. https://doi.org/10.1021/acs.oprd.5b00127
Srai, J. S.; Badman, C.; Krumme, M.; Futran, M.; Johnston, C., Future supply chains enabled by continuous processing--opportunities and challenges. May 20-21, 2014 Continuous Manufacturing Symposium. J Pharm Sci 2015, 104 (3), 840-9. https://doi.org/10.1002/jps.24343
Srai, J. S.; Harrington, T.; Alinaghian, L.; Phillips, M., Evaluating the potential for the continuous processing of pharmaceutical products-a supply network perspective. Chem Eng Process 2015, 97, 248-258. https://doi.org/10.1016/j.cep.2015.07.018
Su, Q. L.; Benyahia, B.; Nagy, Z. K.; Rielly, C. D., Mathematical Modeling, Design, and Optimization of a Multisegment Multiaddition Plug-Flow Crystallizer for Antisolvent Crystallizations. Organic Process Research & Development 2015, 19 (12), 1859-1870. https://doi.org/10.1021/acs.oprd.5b00110
Su, Q. L.; Nagy, Z. K.; Rielly, C. D., Pharmaceutical crystallisation processes from batch to continuous operation using MSMPR stages: Modelling, design, and control. Chem Eng Process 2015, 89 (0), 41-53. https://doi.org/10.1016/j.cep.2015.01.001
Sun, C. C.; Sun, W.; Price, S.; Hughes, C.; Ter Horst, J.; Veesler, S.; Lewtas, K.; Myerson, A.; Pan, H.; Coquerel, G.; van den Ende, J.; Meekes, H.; Mazzotti, M.; Rosbottom, I.; Taulelle, F.; Black, S.; Mackenzie, A.; Janbon, S.; Vekilov, P.; Threlfall, T.; Turner, T.; Back, K.; Cuppen, H.; Toroz, D.; Sefcik, J.; Lovelock, J.; Hammond, R.; Candoni, N.; Simone, E.; Ward, M.; Bertran, C. A.; Vetter, T.; Sear, R.; De Yoreo, J.; Davey, R.; Anwar, J.; Santiso, E.; Wu, D. T.; Roberts, K.; Peters, B.; Schroeder, S.; Jones, F.; Rasmuson, A.; Colfen, H.; Zeglinski, J.; Salvalaglio, M., Solvent and additive interactions as determinants in the nucleation pathway: general discussion. Faraday Discuss 2015, 179 (0), 383-420. https://doi.org/10.1039/C5FD90038G
Sun, W.; Booth, S.; Myerson, A.; Hughes, C.; Pan, H.; Coquerel, G.; Brandel, C.; Meekes, H.; Mazzotti, M.; Fabian, L.; Black, S.; Vekilov, P.; Back, K.; Toroz, D.; Lovelock, J.; Sefcik, J.; Rasmuson, A.; Breynaert, E.; Sear, R.; Hammond, R.; Ward, M.; Threlfall, T.; De Yoreo, J.; Davey, R.; Ristic, R.; Lewtas, K.; Roberts, K.; Hare, A.; Gich, M.; Colfen, H.; Likhatskiy, M.; ter Horst, J.; Sommerdijk, N., Time and space resolved methods: general discussion. Faraday Discuss 2015, 179 (0), 247-67. https://doi.org/10.1039/c5fd90037a
Tachtatzis, C.; Sheridan, R.; Michie, C.; Atkinson, R. C.; Cleary, A.; Dziewierz, J.; Andonovic, I.; Briggs, N. E. B.; Florence, A. J.; Sefcik, J., Image-based monitoring for early detection of fouling in crystallisation processes. Chem Eng Sci 2015, 133, 82-90. https://doi.org/10.1016/j.ces.2015.01.038
ter Horst, J. H.; Schmidt, C.; Ulrich, J., Fundamentals of Industrial Crystallization. In Handbook of Crystal Growth, Rudolph, P., Ed. Elsevier: Boston, 2015; pp 1317-1349. https://doi.org/10.1016/b978-0-444-63303-3.00032-8
Ward, M. R.; Jamieson, W. J.; Leckey, C. A.; Alexander, A. J., Laser-induced nucleation of carbon dioxide bubbles. J Chem Phys 2015, 142 (14), 144501. https://doi.org/10.1063/1.4917022
Ward, M. R.; Rae, A.; Alexander, A. J., Nonphotochemical Laser-Induced Crystal Nucleation by an Evanescent Wave. Crystal Growth & Design 2015, 15 (9), 4600-4605. https://doi.org/10.1021/acs.cgd.5b00854
Wittering, K. E.; Agnew, L. R.; Klapwijk, A. R.; Robertson, K.; Cousen, A. J. P.; Cruickshank, D. L.; Wilson, C. C., Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives. Crystengcomm 2015, 17 (19), 3610-3618. https://doi.org/10.1039/C5CE00297D
Wongpinyochit, T.; Uhlmann, P.; Urquhart, A. J.; Seib, F. P., PEGylated Silk Nanoparticles for Anticancer Drug Delivery. Biomacromolecules 2015, 16 (11), 3712-22. https://doi.org/10.1021/acs.biomac.5b01003
