Publication 2021
Al-Sharabi, M.; Markl, D.; Vivacqua, V.; Bawuah, P.; MacLean, N.; Bentley, M.; York, A. P. E.; Marigo, M.; Huang, K.; Zeitler, J. A., Terahertz pulsed imaging as a new method for investigating the liquid transport kinetics of α-alumina powder compacts. Chemical Engineering Research and Design 2021, 165, 386-397. https://doi.org/10.1016/j.cherd.2020.11.006
Bawuah, P.; Markl, D.; Turner, A.; Evans, M.; Portieri, A.; Farrell, D.; Lucas, R.; Anderson, A.; Goodwin, D. J.; Zeitler, J. A., A Fast and Non-destructive Terahertz Dissolution Assay for Immediate Release Tablets. Journal of Pharmaceutical Sciences 2021, 110 (5), 2083-2092. https://doi.org/10.1016/j.xphs.2020.11.041
Benyahia, B.; Anandan, P. D.; Rielly, C., Control of Batch and Continuous Crystallization Processes using Reinforcement Learning. In Computer Aided Chemical Engineering, Türkay, M.; Gani, R., Eds. Elsevier: 2021; Vol. 50, pp 1371-1376. https://doi.org/10.1016/B978-0-323-88506-5.50211-4
Briggs, N. E. B.; McGinty, J.; McCabe, C.; Raval, V.; Sefcik, J.; Florence, A. J., Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers. ACS Omega 2021, 6 (28), 18352-18363. https://doi.org/10.1021/acsomega.1c02215
Capdevila-Echeverria, J.; Wang, J.; Lakerveld, R.; ter Horst, J. H., Process modeling and optimization of continuous chiral resolution by integration of membrane and crystallization technologies. Journal of Membrane Science 2021, 632, 119359. https://doi.org/10.1016/j.memsci.2021.119359
Deng, T.; Garg, V.; Bradley, M. S. A., A study of particle adhesion for cohesive powders using a novel mechanical surface energy tester. Powder Technology 2021, 391, 46-56. https://doi.org/10.1016/j.powtec.2021.06.002
Edwards, P. T.; Saunders, L. K.; Pallipurath, A. R.; Britton, A. J.; Willneff, E. A.; Shotton, E. J.; Schroeder, S. L. M., Proton Transfer on the Edge of the Salt/Cocrystal Continuum: X-Ray Photoelectron Spectroscopy of Three Isonicotinamide Salts. Crystal Growth & Design 2021, 21 (11), 6332-6340. https://doi.org/10.1021/acs.cgd.1c00807
Febra, S. A.; Bernet, T.; Mack, C.; McGinty, J.; Onyemelukwe, I. I.; Urwin, S. J.; Sefcik, J.; ter Horst, J. H.; Adjiman, C. S.; Jackson, G.; Galindo, A., Extending the SAFT-γ Mie approach to model benzoic acid, diphenylamine, and mefenamic acid: solubility prediction and experimental measurement. Fluid Phase Equilibria 2021, 113002. https://doi.org/10.1016/j.fluid.2021.113002
Jones, E. C. L.; Bebiano, S. S.; Ward, M. R.; Bimbo, L. M.; Oswald, I. D. H., Pressure-induced superelastic behaviour of isonicotinamide. Chem Commun (Camb) 2021, 57 (89), 11827-11830. https://doi.org/10.1039/D1CC04692F
Kaur Aulakh, P.; Settanni, E.; Srai, J. S., Multi-Criteria Assessment of Continuous Manufacturing Reactor Technologies in Upstream Pharmaceutical Supply Chains. SSRN Electronic Journal 2021. https://doi.org/10.2139/ssrn.3884025
Maclean, N.; Walsh, E.; Soundaranathan, M.; Khadra, I.; Mann, J.; Williams, H.; Markl, D., Exploring the performance-controlling tablet disintegration mechanisms for direct compression formulations. International Journal of Pharmaceutics 2021, 599, 120221. https://doi.org/10.1016/j.ijpharm.2021.120221
Markl, D.; Maclean, N.; Mann, J.; Williams, H.; Abbott, A.; Mead, H.; Khadra, I., Tablet disintegration performance: Effect of compression pressure and storage conditions on surface liquid absorption and swelling kinetics. International Journal of Pharmaceutics 2021, 601, 120382. https://doi.org/10.1016/j.ijpharm.2021.120382
Ottoboni, S.; Wareham, B.; Vassileiou, A.; Robertson, M.; Brown, C. J.; Johnston, B.; Price, C. J., A Novel Integrated Workflow for Isolation Solvent Selection Using Prediction and Modeling. Organic Process Research & Development 2021. https://doi.org/10.1021/acs.oprd.0c00532
Pallipurath, A. R.; Skelton, J. M.; Britton, A.; Willneff, E. A.; Schroeder, S. L. M., Bulk and Surface Conformations in Solid-State Lovastatin: Spectroscopic and Molecular Dynamics Studies. Crystals 2021, 11 (5), 509. https://doi.org/10.3390/cryst11050509
Rodrigues, M. A.; Rego, P.; Geraldes, V.; Connor, L. E.; Oswald, I. D. H.; Sztucki, M.; Shalaev, E., Mannitol Crystallization at Sub-Zero Temperatures: Time/Temperature-Resolved Synchrotron X-ray Diffraction Study and the Phase Diagram. J Phys Chem Lett 2021, 12 (5), 1453-1460. https://doi.org/10.1021/acs.jpclett.0c03680
Saunders, L. K.; Pallipurath, A. R.; Gutmann, M. J.; Nowell, H.; Zhang, N.; Allan, D. R., A quantum crystallographic approach to short hydrogen bonds. CrystEngComm 2021, 23 (35), 6180-6190. https://doi.org/10.1039/D1CE00355K
Shahid, M.; Sanxaridou, G.; Ottoboni, S.; Lue, L.; Price, C., Exploring the Role of Anti-solvent Effects during Washing on Active Pharmaceutical Ingredient Purity. Organic Process Research & Development 2021, 25 (4), 969-981. https://doi.org/10.1021/acs.oprd.1c00005
Sheridan, R.; Cardona, J.; Tachtatzis, C.; Chen, Y.-C.; Cleary, A.; Briggs, N.; Florence, A.; Atkinson, R.; Michie, C.; Andonovic, I.; Sefcik, J., Effect of oscillatory flow conditions on crystalliser fouling investigated through non-invasive imaging. Chem Eng Sci 2021, 117188. https://doi.org/10.1016/j.ces.2021.117188
Stranzinger, S.; Markl, D.; Khinast, J. G.; Paudel, A., Review of sensing technologies for measuring powder density variations during pharmaceutical solid dosage form manufacturing. TrAC Trends in Analytical Chemistry 2021, 135, 116147. https://doi.org/10.1016/j.trac.2020.116147
Urwin, S. J.; Yerdelen, S.; Houson, I.; ter Horst, J. H., Impact of Impurities on Crystallization and Product Quality: A Case Study with Paracetamol. Crystals 2021, 11 (11), 1344. https://doi.org/10.3390/cryst11111344
Verma, L.; Warzecha, M.; Chakrabarti, R.; Hadjiev, V. G.; Palmer, J. C.; Vekilov, P. G., How to Identify the Crystal Growth Unit. Israel Journal of Chemistry 2021, 61 (11-12), 818-827. https://doi.org/10.1002/ijch.202100081
Warzecha, M.; Florence, A. J.; Vekilov, P. G., The Ambiguous Functions of the Precursors That Enable Nonclassical Modes of Olanzapine Nucleation and Growth. Crystals 2021, 11 (7), 738. https://doi.org/10.3390/cryst11070738
Watson, O. L.; Jonuzaj, S.; McGinty, J.; Sefcik, J.; Galindo, A.; Jackson, G.; Adjiman, C. S., Computer Aided Design of Solvent Blends for Hybrid Cooling and Antisolvent Crystallization of Active Pharmaceutical Ingredients. Organic Process Research & Development 2021, 25 (5), 1123-1142. https://doi.org/10.1021/acs.oprd.0c00516
Yang, Y.; Ahmed, B.; Mitchell, C.; Quon, J. L.; Siddique, H.; Houson, I.; Florence, A. J.; Papageorgiou, C. D., Investigation of Wet Milling and Indirect Ultrasound as Means for Controlling Nucleation in the Continuous Crystallization of an Active Pharmaceutical Ingredient. Organic Process Research & Development 2021 , 25 (9), 2119-2132. https://doi.org/10.1021/acs.oprd.1c00209
