X-Ray and Solid-State
An integrated hub for mapping the full solid‑state landscape, uniting advanced X‑ray analysis with experimental expertise.
About
CMAC is a leader in advanced X-Ray and solid-state analysis, uniquely combining analytical capabilities with experimental preparation in a single, integrated environment. This approach enables seamless collaboration with both commercial and academic partners, primarily in medicines manufacturing, but also across a wide range of application areas.
What sets us apart is our ability to map the entire solid-state landscape using a fully integrated suite of predictive and measurement tools. Coupled with a single, multidisciplinary team of academic experts and state-of-the-art infrastructure, our National Facility is the go-to hub for solid-state research and innovation.
Our Services:
Our crystallographers and solid-state specialists provide integrated, problem‑focused studies that go beyond standalone measurements, connecting structural insights directly to product performance and manufacturability.
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More info coming soon
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More info coming soon
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More info coming soon
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More info coming soon
High‑Performance X‑ray & Solid-State Platforms
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Single crystal X-Ray diffraction
High-quality single crystal structure determination for small molecules, salts, cocrystals, solvates & polymorphs.
Temperature-dependent studies, & custom crystallographic services, including data collection, refinement, and collaborative projects.
Cu and Mo X-ray sources with precise temperature control (80–400 K), supporting challenging samples and weakly diffracting crystals.
Insitu High pressure crystallography (Diamond anvil cell; pressures ca. ambient – 10 GPa).
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Powder X-Ray diffraction
Phase identification, phase purity assessment, quantitative phase analysis, and ab initio structure solution from powder data.
In situ and non-ambient PXRD under controlled temperature, humidity, gas flow, or vacuum to study phase transformations and stability.
High-throughput screening using multi-well plates for rapid data collection.
Reflection and transmission (capillary, Cu Kα₁) geometries enabling surface-sensitive measurements and high-resolution structural analysis of pharmaceutical solids.
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X-Ray pair distribution function (xPDF)
Mo-source provides total scattering measurements, wide Q-range, & variable temperature control (80–500 K).
Pair distribution function (xPDF) analysis revealing local and short-range order in crystalline, nanocrystalline, and amorphous pharmaceutical materials.
Powerful for studying poorly crystalline phases, nanomaterials, disorder, and early-stage solid forms inaccessible by conventional PXRD.
Temperature-dependent xPDF studies to probe structural changes, relaxation, and amorphous–crystalline transitions.
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X-Ray nano-computed tomography (nano-CT)
Bruker SkyScan 2214 provides non-destructive 3D imaging of materials, from sub-micron features to whole devices.
High-resolution scanning (~300–500 nm), multiscale analysis, and quantitative assessment of morphology, porosity, particle size, cracks, and defects.
In situ options include heating, cooling, and mechanical testing.
Ideal for studying pharmaceuticals, composites, medical devices, low-density or multi-material systems, and failure analysis, giving detailed insights across a range of sample sizes.
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Small and wide-angle X-Ray scattering (SAXS/WAXS)
Xenocs Xeuss 2.0 SAXS/WAXS.
Quantitative analysis of particle size, shape, aggregation, and internal organisation across length scales from ~0.1–100 nm.
Simultaneous SAXS and WAXS measurements for hierarchical structural analysis, linking nanoscale organisation with crystalline structure.
In situ environments (temperature, humidity, shear/flow) supporting dynamic studies of formulations and devices.
Nanoparticle and polymer characterisation, domain spacing analysis, extended q-range measurements and XRD mapping for nanostructure and crystalline domains.
