Publication 2018

Agimelen, O. S.; Svoboda, V.; Ahmed, B.; Cardona, J.; Dziewierz, J.; Brown, C. J.; McGlone, T.; Cleary, A.; Tachtatzis, C.; Michie, C.; Florence, A. J.; Andonovic, I.; Mulholland, A. J.; Sefcik, J., Multi-sensor inline measurements of crystal size and shape distributions during high shear wet milling of crystal slurries. Advanced Powder Technology 2018, 29, 2987-2995. https://doi.org/10.1016/j.apt.2018.09.003

Al-Madhagi, L. H.;  Chang, S.-Y.;  Balasubramanian, M.;  Kroner, A. B.;  Shotton, E. J.;  Willneff, E. A.;  Mishra, B.; Schroeder, S. L. M., X-ray Raman scattering: a new in situ probe of molecular structure during nucleation and crystallization from liquid solutions. CrystEngComm 2018, 20 (43), 6871-6884.  https://doi.org/10.1039/C8CE00929E

Bhardwaj, R. M.; Reutzel-Edens, S. M.; Johnston, B. F.; Florence, A. J., A random forest model for predicting crystal packing of olanzapine solvates. CrystEngComm 2018, 20, 3947-3950. https://doi.org/10.1039/C8CE00261D

Bouvart, N.; Palix, R.-M.; Arkhipov, S. G.; Tumanov, I. A.; Michalchuk, A. A. L.; Boldyreva, E. V., Polymorphism of chlorpropamide on liquid-assisted mechanical treatment: choice of liquid and type of mechanical treatment matter. CrystEngComm 2018. DOI: 10.1039/C7ME00096K

Brown, C. J.; McGlone, T.; Yerdelen, S.; Srirambhatla, V.; Mabbott, F.; Gurung, R.; L. Briuglia, M.; Ahmed, B.; Polyzois, H.; McGinty, J.; Perciballi, F.; Fysikopoulos, D.; MacFhionnghaile, P.; Siddique, H.; Raval, V.; Harrington, T. S.; Vassileiou, A. D.; Robertson, M.; Prasad, E.; Johnston, A.; Johnston, B.; Nordon, A.; Srai, J. S.; Halbert, G.; ter Horst, J. H.; Price, C. J.; Rielly, C. D.; Sefcik, J.; Florence, A. J., Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations. Molecular Systems Design & Engineering 2018.  DOI: 10.1039/C7ME00096K

Burcham, C. L.; Florence, A. J.; Johnson, M. D., Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing. Annual Review of Chemical and Biomolecular Engineering 2018, 9, 253-281. https://doi.org/10.1146/annurev-chembioeng-060817-084355

Cardona, J.; Ferreira, C.; McGinty, J.; Hamilton, A.; Agimelen, O. S.; Cleary, A.; Atkinson, R.; Michie, C.; Marshall, S.; Chen, Y.-C.; Sefcik, J.; Andonovic, I.; Tachtatzis, C., Image analysis framework with focus evaluation for in situ characterisation of particle size and shape attributes. Chemical Engineering Science 2018, 191, 208-231. https://doi.org/10.1016/j.ces.2018.06.067

Case, D. H.; Srirambhatla, V. K.; Guo, R.; Watson, R. E.; Price, L. S.; Polyzois, H.; Cockcroft, J. K.; Florence, A. J.; Tocher, D. A.; Price, S. L., Successful Computationally Directed Templating of Metastable Pharmaceutical Polymorphs. Crystal Growth & Design 2018, 18, 5322-5331. DOI: 10.1021/acs.cgd.8b00765

Doerr, F. J. S.; Oswald, I. D. H.; Florence, A. J., Quantitative investigation of particle formation of a model pharmaceutical formulation using single droplet evaporation experiments and X-ray tomography. Advanced Powder Technology 2018. DOI: 10.1016/j.apt.2018.09.027

Forbes, C.; Nguyen, T.T.H; O'Leary, R.L.; Price, C.J., Elucidating the mechanism of paracetamol sonocrystallization for product purity enhancement.   Proceedings of Meetings on Acoustics, 2018 32, ICU2017 - 287. https://asa.scitation.org/doi/abs/10.1121/2.0000739

Harrington, T. S.; Burge, T. A., Connecting digital pharma and e-healthcare value networks through product-service design: a conceptual model. International Journal of Electronic Healthcare 2018, 10 (1-2), 96-129.   https://doi.org/10.1504/IJEH.2018.092177

Harrington, T. S.;  Srai, J. S.; Najim, I., Emerging product-process archetypes in oncology: informing the sustainable provision of next-generation medicines. International Journal of Healthcare Technology and Management 2018, 17 (2-3), 97-127.  https://doi.org/10.1504/Ijhtm.2018.098367

Hatcher, L.; CCDC 1829765: Experimental Crystal Structure Determination, 2018, DOI: 10.5517/ccdc.csd.cc1zf0p3

Jiang, M.; Ni, X.-W., Effects of water and temperature on reaction mechanism and crystal properties in a reactive crystallization of paracetamol. Chemical Engineering and Processing - Process Intensification 2018, 131, 20-26. https://doi.org/10.1016/j.cep.2018.07.006

Jimeno, G.; Lee, Y. C.; Ni, X.-W., On the evaluation of power density models for oscillatory baffled reactors using CFD. Chemical Engineering and Processing - Process Intensification 2018, 134, 153-162. DOI: 10.1016/j.cep.2018.11.002 https://doi.org/10.1016/j.cep.2018.11.002

Kathyola, T., In situ monitoring of the reactive crystallization of calcium carbonate in multiphase systems. In 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, Abstracts of Papers Of The American Chemical Society: 2018; Vol. 255.

Kongsamai, P.;  Flood, C.;  ter Horst, J. H.; Flood, A. E., Particle Size Distributions and Performance of Preferential Crystallization of L-Asparagine·H2O with Tailor-Made Additives. Chemical Engineering & Technology 2018, 41 (6), 1173-1179. https://doi.org/10.1002/ceat.201700668

Laskar, P.;  Somani, S.;  Altwaijry, N.;  Mullin, M.;  Bowering, D.;  Warzecha, M.;  Keating, P.;  Tate, R. J.;  Leung, H. Y.; Dufès, C., Redox-sensitive, cholesterol-bearing PEGylated poly(propylene imine)-based dendrimersomes for drug and gene delivery to cancer cells. Nanoscale 2018, 10 (48), 22830-22847.  https://doi.org/10.1039/C8NR08141G  

Lin, H.; Zhang, Z.; Markl, D.; Zeitler, J. A.; Shen, Y., A Review of the Applications of OCT for Analysing Pharmaceutical Film Coatings. Applied Sciences 2018, 8, 2700. DOI: 10.3390/app8122700  https://doi.org/10.3390/app8122700

McLaughlin, A,M.; Robertson, J.; Ni,  X., Material characterisation and parameter effects on bulk solid dissolution rate of paracetamol in a stirred tank vessel using an in situ UV-ATR probe. International Journal of Engineering Research & Science. 2018, 4(1):10-20.

Michalchuk, A. A. L.; Hope, K. S.; Kennedy, S. R.; Blanco, M.; Boldyreva, E.; Pulham, C. R., Ball-Free Mechanochemistry: In Situ Real-Time Monitoring of Pharmaceutical Co-Crystal Synthesis by Resonant Acoustic Mixing. Chemical Communications 2018. https://doi.org/10.1039/C8CC02187B

Michalchuk, A. A. L.; Fincham, P. T.; Portius, P.; Pulham, C. R.; Morrison, C. A., A Pathway to the Athermal Impact Initiation of Energetic Azides. The Journal of Physical Chemistry C 2018, 122, 19395-19408.  https://doi.org/10.1021/acs.jpcc.8b05285

Michalchuk, A. A. L.;  Rudić, S.;  Pulham, C. R.; Morrison, C. A., Vibrationally induced metallisation of the energetic azide α-NaN3. Physical Chemistry Chemical Physics 2018, 20 (46), 29061-29069. https://doi.org/10.1039/C8CP06161K

Michalchuk, A. A. L.;  Tumanov, I. A.; Boldyreva, E. V., The effect of ball mass on the mechanochemical transformation of a single-component organic system: anhydrous caffeine. Journal of Materials Science 2018, 53 (19), 13380-13389. https://doi.org/10.1007/s10853-018-2324-2

Neugebauer, P.; Cardona, J.; Besenhard, M. O.; Peter, A.; Gruber-Woelfler, H.; Tachtatzis, C.; Cleary, A.; Andonovic, I.; Sefcik, J.; Khinast, J. G., Crystal Shape Modification via Cycles of Growth and Dissolution in a Tubular Crystallizer. Crystal Growth & Design 2018. DOI: 10.1021/acs.cgd.8b00371

Onyemelukwe, I. I.; Benyahia, B.; Reis, N. M.; Nagy, Z. K.; Rielly, C. D., The heat transfer characteristics of a mesoscale continuous oscillatory flow crystalliser with smooth periodic constrictions. International Journal of Heat and Mass Transfer 2018, 123, 1109-1119. DOI: 10.1016/j.ijheatmasstransfer.2018.03.015

Onyemelukwe, I.I.; Parsons, A.R.; Wheatcroft, H.P.; Robertson, A.; Nagy, Z.K.; Rielly, C.D. The role of residence time distribution in the continuous steady-state MSMPR crystallization of glycine. Crystal Growth & Design 2018, DOI: 10.1021/acs.cgd.8b00853

Ottoboni, S.; Chrubasik, M.; Mir Bruce, L.; Nguyen, T. T. H.; Robertson, M.; Johnston, B.; Oswald, I. D. H.; Florence, A.; Price, C., Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS. Crystal Growth & Design 2018, 18, 2750-2758. DOI: 10.1021/acs.cgd.7b01411

Ottoboni, S.; Price, C. J.; Steven, C.; Meehan, E.; Barton, A.; Firth, P.; Mitchell, A.; Tahir, F., Development of a Novel Continuous Filtration Unit for Pharmaceutical Process Development and Manufacturing. Journal of pharmaceutical sciences 2018. DOI: 10.1016/j.xphs.2018.07.005

Parekh, R.;  Benyahia, B.; Rielly, C. D., A Global State Feedback Linearization and Decoupling MPC of a MIMO Continuous MSMPR Cooling Crystallization Process. In Computer Aided Chemical Engineering, Friedl, A.;  Klemeš, J. J.;  Radl, S.;  Varbanov, P. S.; Wallek, T., Eds. Elsevier: 2018; Vol. 43, pp 1607-1612. https://doi.org/10.1016/B978-0-444-64235-6.50280-1

Phillips, M. A.; Srai, J. S., Exploring Emerging Ecosystem Boundaries: Defining ‘The Game’. International Journal of Innovation Management 2018, 22 (08), 1840012.  https://doi.org/10.1142/s1363919618400121

Pitt, K.; Peña, R.; Tew, J. D.; Pal, K.; Smith, R.; Nagy, Z. K.; Litster, J. D., Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling. Powder Technology 2017. https://doi.org/10.1016/j.powtec.2017.11.052

Scott, C. D.; Labes, R.; Depardieu, M.; Battilocchio, C.; Davidson, M. G.; Ley, S. V.; Wilson, C. C.; Robertson, K., Integrated plug flow synthesis and crystallisation of pyrazinamide. Reaction Chemistry & Engineering 2018, 3, 631-634. DOI: 10.1039/C8RE00087E

Settanni, E., Srai, J., & Kothapalli, V. M. , Combining field data analysis and simulation to evaluate an alternative Just-In-Time clinical trial supply strategy. 22nd Cambridge International Manufacturing Symposium. 2018. https://doi.org/10.17863/CAM.33388

Settanni, E.S.; Srai, J., Digitalisation of the UK Manufacturing Economy: Structural Dependencies and Implications for Intervention Strategies.  SSRN Electronic Journal,  2018. https://doi.org/10.2139/ssrn.3292258

Settanni, E. S., Srai J., Towards a new approach to modelling pharmaceutical supply chains in a changing technological landscape. Pharma Horizon 2018, 2 (1), 26-28.  https://www.teknoscienze.com/tks_article/towards-a-new-approach-to-modelling-pharmaceutical-supply-chains-in-a-changing-technological-landscape/

Settanni, E., Srai, J., & Kothapalli, V. M.  Combining field data analysis and simulation to evaluate an alternative Just-In-Time clinical trial supply strategy.  22nd Cambridge International Manufacturing Symposium.  https://doi.org/10.17863/CAM.33388

Steendam, R. R. E.; ter Horst, J. H., Scaling Up Temperature Cycling-Induced Deracemization by Suppressing Nonstereoselective Processes. Crystal Growth & Design 2018, 18, 3008-3015. https://doi.org/10.1021/acs.cgd.8b00121

Tsolakis, N.; Srai, J. S., Mapping supply dynamics in renewable feedstock enabled industries: A systems theory perspective on "green' pharmaceuticals. Operations Management Research 2018, 11 (3-4), 83-104. https://doi.org/10.1007/s12063-018-0134-y

Turner, T. D.; Hatcher, L. E.; Wilson, C. C.; Roberts, K. J., Habit Modification of the API Lovastatin through a Predictive Solvent Selection Approach. Journal of pharmaceutical sciences 2018.  https://doi.org/10.1016/j.xphs.2018.12.012

Turner, T. D.; Lai, X.; Roberts, K. J., The thermal expansion coefficients of the alpha and beta polymorphic forms of p-aminobenzoic acid in relation to their bulk crystal chemistry. CrystEngComm 2018, 20, 4099-4102. DOI: 10.1039/C8CE00539G

Wongpinyochit, T.; Johnston, B. F.; Seib, F. P., Degradation Behavior of Silk Nanoparticles—Enzyme Responsiveness. ACS Biomaterials Science & Engineering 2018, 4, 942-951. DOI: 10.1021/acsbiomaterials.7b01021