Amparo Galindo

Professor of Physical Chemistry, Imperial College’s Institute for Molecular and Science and Engineering Co-Director

Imperial College London

Amparo trained as a physical chemist at the Universidad Complutense of Madrid (BSc) and University of Sheffield (PhD), then joined the Department of Chemical Engineering in Imperial as a member of academic staff. Amparo has been a professor of Physical Chemistry in Imperial since 2011 and has been part of CMAC since 2017.

Amparo’s group leads the development of molecular approaches for the prediction of properties of complex fluids. In CMAC we contribute to the development of the SAFT-γ Mie approach for the prediction of solubility of active pharmaceutical ingredients (APIs) in different solvents and mixed environments. The SAFT-γ Mie equation is a high-fidelity approach that accounts for the contributions of molecular length, molecular association (hydrogen bonding), electrostatic interactions, and dispersion forces; considered the state-of-the-art approach for property prediction in complex fluids and which forms the basis of commercial available code distributed via Process Systems Enterprise (PSE). We are also interested in fundamental developments linking progress at the quantum mechanical level with analytical predictive approaches that can be formulated in the solvent design environment. The translation of quantum mechanical outputs, mostly related to single molecule characteristics, to statistical mechanics frameworks, which concern to bulk properties is far from trivial. The fruit of this work is leading to major step-changes in ab-initio solvent design for reactions.