CMAC Publications


2020

Pallipurath, A. R.;  Flandrin, P.-B.;  Wayment, L. E.;  Wilson, C. C.; Robertson, K., In situ non-invasive Raman spectroscopic characterisation of succinic acid polymorphism during   segmented flow crystallisation. Molecular Systems Design & Engineering 2020. https://doi.org/10.1039/C9ME00103D


2019

Arjmandi-Tash, O.;  Tew, J. D.;  Pitt, K.;  Smith, R.; Litster, J. D., A new mathematical model for nucleation of spherical agglomerates by the immersion mechanism. Chemical Engineering Science: X 2019, 4, 100048 https://doi.org/10.1016/j.cesx.2019.100048

Briuglia, M. L.; Sefcik, J.; ter Horst, J. H., Measuring Secondary Nucleation through Single Crystal Seeding. Crystal Growth & Design 2019, 19, 421-429. https://doi.org/10.1021/acs.cgd.8b01515

Bordos, E.; Islam, M. T.; Florence, A. J.; Halbert, G. W.; Robertson. Use of Terahertz-Raman Spectroscopy to Determine Solubility of the Crystalline Active Pharmaceutical Ingredient in Polymeric Matrices during Hot Melt Extrusion J. Molecular Pharmaceutics 2019, 16, 4361.  https://doi.org/10.1021/acs.molpharmaceut.9b00703

Connor, L. E.; Vassileiou, A. D.; Halbert, G. W.; Johnston, B. F.; Oswald, I. D. H., Structural investigation and compression of a co-crystal of indomethacin and saccharin. CrystEngComm 2019. https://doi.org/10.1039/C9CE00838A  

Dunn, A. S.; Svoboda, V.; Sefcik, J.; ter Horst. Resolution control in a continuous preferential crystallization process. Organic Process Research & Development, 2019 23 (9), 2031-2041. https://doi.org/10.1021/acs.oprd.9b00275

Edinger, M.; Iftimi, L.-D.; Markl, D.; Al-Sharabi, M.; Bar-Shalom, D.; Rantanen, J.; Genina, N., Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy. AAPS PharmSciTech 2019, 20, 207. https://doi.org/10.1208/s12249-019-1423-y

Jiang, M.; Ni, X.-W., Reactive Crystallization of Paracetamol in a Continuous Oscillatory Baffled Reactor. Organic Process Research & Development 2019, 23, 882-890. https://doi.org/10.1016/j.ijpharm.2018.12.052

Jiang, M.; Ni, X.-W., Effects of solvents and impurity on crystallization kinetics and crystal properties in a reactive crystallization of paracetamol. Journal of Crystal Growth 2019, 523, 125150. https://doi.org/10.1016/j.jcrysgro.2019.125150

Jimeno, G.; Lee, Y. C.; Ni, X.-W., Smoothed particle hydrodynamics – A new approach for modeling flow in oscillatory baffled reactors. Computers & Chemical Engineering 2019, 124, 14-27. https://doi.org/10.1016/j.cep.2018.11.002

Jolliffe, H. G.;  Papathanasiou, F.;  Prasad, E.;  Halbert, G.;  Robertson, J.;  Brown, C. J.; Florence, A. J., Improving the prediction of multi-component tablet properties from pure component parameters. In Computer Aided Chemical Engineering, Kiss, A. A.;  Zondervan, E.;  Lakerveld, R.; Özkan, L., Eds. Elsevier: 2019; Vol. 46, pp 883-888. https://doi.org/10.1016/B978-0-12-818634-3.50148-X

Marathe, S.;  Storm, M.;  Kuppilli, V. S. C.;  Harrison, R.;  Das, G.;  Schroeder, S. L. M.;  Cipiccia, S.;  Döring, F.;  David, C.; Rau, C., Development of synchrotron pink beam x-ray grating interferometer at the Diamond Light source I13-2 beamline. SPIE: 2019; Vol. 11113. https://doi.org/10.1117/12.2530698 

Mendez Torrecillas, C.; Gorringe, L. J.; Rajoub, N.; Robertson, J.; Elkes, R. G.; Lamprou, D. A.; Halbert, G. W., The impact of channel fill level on internal forces during continuous twin screw wet granulation. International journal of pharmaceutics 2019, 558, 91-100. https://doi.org/10.1016/j.ijpharm.2018.12.052

Onyemelukwe, I., Nagy, Z.K., Rielly, C.D. 2019. Solid-liquid axiald dispersion performance of a mesoscale continuous oscillatory flow crystalliser with smooth periodic constrictions using a non-invasive dual backlit imaging technique, Chem. Eng. J.  2019 https://doi.org/10.1016/j.cej.2019.122862

Onyemelukwe, I. I.; Parsons, A. R.; Wheatcroft, H. P.; Robertson, A.; Nagy, Z. K.; Rielly, C. D., The Role of Residence Time Distribution in the Continuous Steady-State Mixed Suspension Mixed Product Removal Crystallization of Glycine. Crystal Growth & Design 2019, 19, 66-80. https://pubs.acs.org/doi/10.1021/acs.cgd.8b00853

Prasad, E.; Islam, M. T.; Goodwin, D. J.; Megarry, A. J.; Halbert, G. W.; Florence, A. J.; Robertson, J., Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for fused filament fabrication (FFF) 3D printing. Additive Manufacturing 2019, 29, 100776. https://doi.org/10.1016/j.addma.2019.06.027

Stranzinger, S.; Faulhammer, E.; Li, J.; Dong, R.; Khinast, J. G.; Zeitler, J. A.; Markl, D., Measuring bulk density variations in a moving powder bed via terahertz in-line sensing. Powder Technology 2019, 344, 152-160. DOI: 10.1016/j.powtec.2018.11.106 https://doi.org/10.1016/j.powtec.2018.11.106   

Tahir, F.;  Islam, M. T.;  Mack, J.;  Robertson, J.; Lovett, D., Process monitoring and fault detection on a hot-melt extrusion process using in-line Raman spectroscopy and a hybrid soft sensor. Computers & Chemical Engineering 2019, 125, 400-414. https://doi.org/10.1016/j.compchemeng.2019.03.019

Vesga, M. J.; McKechnie, D.; Mulheran, P. A.; Johnston, K.; Sefcik, J., Conundrum of γ glycine nucleation revisited: to stir or not to stir? CrystEngComm 2019, 21, 2234-2243. https://doi.org/10.1039/C8CE01829D

Ward, M. R.; Oswald, I. D. H., Antisolvent addition at extreme conditions. CrystEngComm 2019. https://doi.org/10.1039/C9CE00365G  

Watson, O. L.;  Galindo, A.;  Jackson, G.; Adjiman, C. S., Computer-aided Design of Solvent Blends for the Cooling and Anti-solvent Crystallisation of Ibuprofen. In Computer Aided Chemical Engineering, Kiss, A. A.;  Zondervan, E.;  Lakerveld, R.; Özkan, L., Eds. Elsevier: 2019; Vol. 46, pp 949-954 https://doi.org/10.1016/B978-0-12-818634-3.50159-4

Wongpinyochit, T.;  Vassileiou, A. D.;  Gupta, S.;  Mushrif, S. H.;  Johnston, B. F.; Seib, F. P., Unraveling the Impact of High-Order Silk Structures on Molecular Drug Binding and Release Behaviors. The Journal of Physical Chemistry Letters 2019, 10 (15), 4278-4284. https://doi.org/10.1021/acs.jpclett.9b01591

Zimbitas, G.; Jawor-Baczynska, A.; Vesga, M. J.; Javid, N.; Moore, B. D.; Parkinson, J.; Sefcik, J. Investigation of molecular and mesoscale clusters in undersaturated glycine aqueous solutions. Colloids and Surfaces A, 2019 579, 123633. https://doi.org/10.1016/j.colsurfa.2019.123633



2018

Agimelen, O. S.; Svoboda, V.; Ahmed, B.; Cardona, J.; Dziewierz, J.; Brown, C. J.; McGlone, T.; Cleary, A.; Tachtatzis, C.; Michie, C.; Florence, A. J.; Andonovic, I.; Mulholland, A. J.; Sefcik, J., Multi-sensor inline measurements of crystal size and shape distributions during high shear wet milling of crystal slurries. Advanced Powder Technology 2018, 29, 2987-2995. https://doi.org/10.1016/j.apt.2018.09.003

Ahmed, B.; Brown, C. J.; McGlone, T.; Bowering, D. L.; Sefcik, J.; Florence, A. J., Engineering of acetaminophen particle attributes using a wet milling crystallisation platform. International journal of pharmaceutics 2019, 554, 201-211 DOI: 10.1016/j.ijpharm.2018.10.073

Bhardwaj, R. M.; Reutzel-Edens, S. M.; Johnston, B. F.; Florence, A. J., A random forest model for predicting crystal packing of olanzapine solvates. CrystEngComm 2018, 20, 3947-3950. DOI:10.1039/C8CE00261D
Bouvart, N.; Palix, R.-M.; Arkhipov, S. G.; Tumanov, I. A.; Michalchuk, A. A. L.; Boldyreva, E. V., Polymorphism of chlorpropamide on liquid-assisted mechanical treatment: choice of liquid and type of mechanical treatment matter. CrystEngComm 2018. DOI: 10.1039/C7ME00096K

Brown, C. J.; McGlone, T.; Yerdelen, S.; Srirambhatla, V.; Mabbott, F.; Gurung, R.; L. Briuglia, M.; Ahmed, B.; Polyzois, H.; McGinty, J.; Perciballi, F.; Fysikopoulos, D.; MacFhionnghaile, P.; Siddique, H.; Raval, V.; Harrington, T. S.; Vassileiou, A. D.; Robertson, M.; Prasad, E.; Johnston, A.; Johnston, B.; Nordon, A.; Srai, J. S.; Halbert, G.; ter Horst, J. H.; Price, C. J.; Rielly, C. D.; Sefcik, J.; Florence, A. J., Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations. Molecular Systems Design & Engineering 2018.  DOI: 10.1039/C7ME00096K

Burcham, C. L.; Florence, A. J.; Johnson, M. D., Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing. Annual Review of Chemical and Biomolecular Engineering 2018, 9, 253-281. https://doi.org/10.1146/annurev-chembioeng-060817-084355

Cardona, J.; Ferreira, C.; McGinty, J.; Hamilton, A.; Agimelen, O. S.; Cleary, A.; Atkinson, R.; Michie, C.; Marshall, S.; Chen, Y.-C.; Sefcik, J.; Andonovic, I.; Tachtatzis, C., Image analysis framework with focus evaluation for in situ characterisation of particle size and shape attributes. Chemical Engineering Science 2018, 191, 208-231. https://doi.org/10.1016/j.ces.2018.06.067

Case, D. H.; Srirambhatla, V. K.; Guo, R.; Watson, R. E.; Price, L. S.; Polyzois, H.; Cockcroft, J. K.; Florence, A. J.; Tocher, D. A.; Price, S. L., Successful Computationally Directed Templating of Metastable Pharmaceutical Polymorphs. Crystal Growth & Design 2018, 18, 5322-5331. DOI: 10.1021/acs.cgd.8b00765

Doerr, F. J. S.; Oswald, I. D. H.; Florence, A. J., Quantitative investigation of particle formation of a model pharmaceutical formulation using single droplet evaporation experiments and X-ray tomography. Advanced Powder Technology 2018. DOI: 10.1016/j.apt.2018.09.027

Forbes, C.; Nguyen, T.T.H; O'Leary, R.L.; Price, C.J., Elucidating the mechanism of paracetamol sonocrystallization for product purity enhancement.   Proceedings of Meetings on Acoustics, 2018 32, ICU2017 - 287. https://asa.scitation.org/doi/abs/10.1121/2.0000739

Hatcher, L.; CCDC 1829765: Experimental Crystal Structure Determination, 2018, DOI: 10.5517/ccdc.csd.cc1zf0p3

Jiang, M.; Ni, X.-W., Effects of water and temperature on reaction mechanism and crystal properties in a reactive crystallization of paracetamol. Chemical Engineering and Processing - Process Intensification 2018, 131, 20-26. DOI: 10.1016/j.cep.2018.07.006

Jimeno, G.; Lee, Y. C.; Ni, X.-W., On the evaluation of power density models for oscillatory baffled reactors using CFD. Chemical Engineering and Processing - Process Intensification 2018, 134, 153-162. DOI: 10.1016/j.cep.2018.11.002 https://doi.org/10.1016/j.cep.2018.11.002

Lin, H.; Zhang, Z.; Markl, D.; Zeitler, J. A.; Shen, Y., A Review of the Applications of OCT for Analysing Pharmaceutical Film Coatings. Applied Sciences 2018, 8, 2700. DOI: 10.3390/app8122700  https://doi.org/10.3390/app8122700

McLaughlin, A,M.; Robertson, J.; Ni,  X., Material characterisation and parameter effects on bulk solid dissolution rate of paracetamol in a stirred tank vessel using an in situ UV-ATR probe. International Journal of Engineering Research & Science. 2018, 4(1):10-20.

Michalchuk, A. A. L.; Hope, K. S.; Kennedy, S. R.; Blanco, M.; Boldyreva, E.; Pulham, C. R., Ball-Free Mechanochemistry: In Situ Real-Time Monitoring of Pharmaceutical Co-Crystal Synthesis by Resonant Acoustic Mixing. Chemical Communications 2018. DOI: 10.1039/C8CC02187B

Michalchuk, A. A. L.; Fincham, P. T.; Portius, P.; Pulham, C. R.; Morrison, C. A., A Pathway to the Athermal Impact Initiation of Energetic Azides. The Journal of Physical Chemistry C 2018, 122, 19395-19408.DOI: 10.1021/acs.jpcc.8b05285

Neugebauer, P.; Cardona, J.; Besenhard, M. O.; Peter, A.; Gruber-Woelfler, H.; Tachtatzis, C.; Cleary, A.; Andonovic, I.; Sefcik, J.; Khinast, J. G., Crystal Shape Modification via Cycles of Growth and Dissolution in a Tubular Crystallizer. Crystal Growth & Design 2018. DOI: 10.1021/acs.cgd.8b00371

Onyemelukwe, I. I.; Benyahia, B.; Reis, N. M.; Nagy, Z. K.; Rielly, C. D., The heat transfer characteristics of a mesoscale continuous oscillatory flow crystalliser with smooth periodic constrictions. International Journal of Heat and Mass Transfer 2018, 123, 1109-1119. DOI: 10.1016/j.ijheatmasstransfer.2018.03.015

Onyemelukwe, I.I.; Parsons, A.R.; Wheatcroft, H.P.; Robertson, A.; Nagy, Z.K.; Rielly, C.D. The role of residence time distribution in the continuous steady-state MSMPR crystallization of glycine. Crystal Growth & Design 2018, DOI: 10.1021/acs.cgd.8b00853

Ottoboni, S.; Chrubasik, M.; Mir Bruce, L.; Nguyen, T. T. H.; Robertson, M.; Johnston, B.; Oswald, I. D. H.; Florence, A.; Price, C., Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS. Crystal Growth & Design 2018, 18, 2750-2758. DOI: 10.1021/acs.cgd.7b01411

Ottoboni, S.; Price, C. J.; Steven, C.; Meehan, E.; Barton, A.; Firth, P.; Mitchell, A.; Tahir, F., Development of a Novel Continuous Filtration Unit for Pharmaceutical Process Development and Manufacturing. Journal of pharmaceutical sciences 2018. DOI: 10.1016/j.xphs.2018.07.005

Parekh, R.;  Benyahia, B.; Rielly, C. D., A Global State Feedback Linearization and Decoupling MPC of a MIMO Continuous MSMPR Cooling Crystallization Process. In Computer Aided Chemical Engineering, Friedl, A.;  Klemeš, J. J.;  Radl, S.;  Varbanov, P. S.; Wallek, T., Eds. Elsevier: 2018; Vol. 43, pp 1607-1612. https://doi.org/10.1016/B978-0-444-64235-6.50280-1

Pitt, K.; Peña, R.; Tew, J. D.; Pal, K.; Smith, R.; Nagy, Z. K.; Litster, J. D., Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling. Powder Technology 2017https://doi.org/10.1016/j.powtec.2017.11.052

Scott, C. D.; Labes, R.; Depardieu, M.; Battilocchio, C.; Davidson, M. G.; Ley, S. V.; Wilson, C. C.; Robertson, K., Integrated plug flow synthesis and crystallisation of pyrazinamide. Reaction Chemistry & Engineering 2018, 3, 631-634. DOI: 10.1039/C8RE00087E

Steendam, R. R. E.; ter Horst, J. H., Scaling Up Temperature Cycling-Induced Deracemization by Suppressing Nonstereoselective Processes. Crystal Growth & Design 2018, 18, 3008-3015. DOI: 10.1021/acs.cgd.8b00121

Turner, T. D.; Hatcher, L. E.; Wilson, C. C.; Roberts, K. J., Habit Modification of the API Lovastatin through a Predictive Solvent Selection Approach. Journal of pharmaceutical sciences 2018. DOI: 10.1016/j.xphs.2018.12.012

Turner, T. D.; Lai, X.; Roberts, K. J., The thermal expansion coefficients of the alpha and beta polymorphic forms of p-aminobenzoic acid in relation to their bulk crystal chemistry. CrystEngComm 2018, 20, 4099-4102. DOI: 10.1039/C8CE00539G

Wongpinyochit, T.; Johnston, B. F.; Seib, F. P., Degradation Behavior of Silk Nanoparticles—Enzyme Responsiveness. ACS Biomaterials Science & Engineering 2018, 4, 942-951. DOI: 10.1021/acsbiomaterials.7b01021



2017

Agimelen, Okpeafoh S., Mulholland, Anthony J., & Sefcik, Jan. (2017). Modelling of artefacts in estimations of particle size of needle-like particles from laser diffraction measurements. Chemical Engineering Science, 158, 445-452. doi: http://dx.doi.org/10.1016/j.ces.2016.10.031

Agnew, Lauren R., McGlone, Thomas, Wheatcroft, Helen P., Robertson, Amy, Parsons, Anna R., & Wilson, Chick C. (2017). Continuous Crystallization of Paracetamol (Acetaminophen) Form II: Selective Access to a Metastable Solid Form. Crystal Growth & Design, 17(5), 2418-2427. doi: 10.1021/acs.cgd.6b01831

Connor, L. E., Morrison, C. A., Oswald, I. D. H., Pulham, C. R., & Warren, M. R. (2017). Carbon dioxide binary crystals via the thermal decomposition of RDX at high pressure. Chemical Science. doi: 10.1039/C7SC01379E

Ejim, Louisa N., Yerdelen, Stephanie, McGlone, Thomas, Onyemelukwe, Iyke, Johnston, Blair, Florence, Alastair J., & Reis, Nuno M. (2017). A factorial approach to understanding the effect of inner geometry of baffled meso-scale tubes on solids suspension and axial dispersion in continuous, oscillatory liquid–solid plug flows. Chemical Engineering Journal, 308, 669-682. doi: http://dx.doi.org/10.1016/j.cej.2016.09.013

Fysikopoulos, D.;  Borsos, A.;  Li, W.;  Onyemelukwe, I.;  Benyahia, B.;  Nagy, Z. K.; Rielly, C. D., Local vs Global Estimability Analysis of Population Balance Models for Crystallization Processes. In Computer Aided Chemical Engineering, Espuña, A.;  Graells, M.; Puigjaner, L., Eds. Elsevier: 2017; Vol. 40, pp 55-60. https://doi.org/10.1016/B978-0-444-63965-3.50011-8

Hall Barrientos, Ivan J., Paladino, Eleonora, Brozio, Sarah, Passarelli, Melissa K., Moug, Susan, Black, Richard A., . . . Lamprou, Dimitrios A. (2017). Fabrication and characterisation of drug-loaded electrospun polymeric nanofibers for controlled release in hernia repair. International Journal of Pharmaceutics, 517(1), 329-337. doi: https://doi.org/10.1016/j.ijpharm.2016.12.022

Hall Barrientos, Ivan J., Paladino, Eleonora, Szabó, Peter, Brozio, Sarah, Hall, Peter J., Oseghale, Charles I., . . . Lamprou, Dimitrios A. (2017). Electrospun collagen-based nanofibres: A sustainable material for improved antibiotic utilisation in tissue engineering applications. International Journal of Pharmaceutics, 531(1), 67-79. doi: https://doi.org/10.1016/j.ijpharm.2017.08.071

Halliwell, Rebecca A., Bhardwaj, Rajni M., Brown, Cameron J., Briggs, Naomi E. B., Dunn, Jaclyn, Robertson, John, . . . Florence, Alastair J. (2017). Spray Drying as a Reliable Route to Produce Metastable Carbamazepine Form IV. Journal of Pharmaceutical Sciences, 106(7), 1874-1880. doi: https://doi.org/10.1016/j.xphs.2017.03.045

Johnston, Andrea, Bhardwaj-Miglani, Rajni, Gurung, Rajesh, Vassileiou, Antony D., Florence, Alastair J., & Johnston, Blair F. (2017). Combined Chemoinformatics Approach to Solvent Library Design Using clusterSim and Multidimensional Scaling. Journal of Chemical Information and Modeling, 57(8), 1807-1815. doi: 10.1021/acs.jcim.7b00038

Kimuli, E. N.;  Onyemelukwe, I. I.;  Benyahia, B.; Rielly, C. D., Characterisation of axial dispersion in a Meso-scale Oscillatory Baffled Crystalliser using a Numerical Approach. In Computer Aided Chemical Engineering, Espuña, A.;  Graells, M.; Puigjaner, L., Eds. Elsevier: 2017; Vol. 40, pp 223-228. https://doi.org/10.1016/B978-0-444-63965-3.50039-8

Kongsamai, Peetikamol, Maneedaeng, Atthaphon, Flood, Chalongsri, ter Horst, Joop H., & Flood, Adrian E. (2017). Effect of additives on the preferential crystallization of L-asparagine monohydrate. The European Physical Journal Special Topics, 226(5), 823-835. doi: 10.1140/epjst/e2016-60257-3

Lau, King Hang Aaron, Castelletto, Valeria, Kendall, Thomas, Sefcik, Jan, Hamley, Ian W., Reza, Mehedi, & Ruokolainen, Janne. (2017). Self-assembly of ultra-small micelles from amphiphilic lipopeptoids. Chemical Communications, 53(13), 2178-2181. doi: 10.1039/C6CC09888F

Liu, Yao, Ward, Martin R., & Alexander, Andrew J. (2017). Polarization independence of laser-induced nucleation in supersaturated aqueous urea solutions. Physical Chemistry Chemical Physics, 19(5), 3464-3467. doi: 10.1039/C6CP07997K

MacFhionnghaile, Pól, Svoboda, Vaclav, McGinty, John, Nordon, Alison, & Sefcik, Jan. (2017). Crystallization Diagram for Antisolvent Crystallization of Lactose: Using Design of Experiments To Investigate Continuous Mixing-Induced Supersaturation. Crystal Growth & Design, 17(5), 2611-2621. doi: 10.1021/acs.cgd.7b00136

Maitz, Manfred F., Sperling, Claudia, Wongpinyochit, Thidarat, Herklotz, Manuela, Werner, Carsten, & Seib, F. Philipp. (2017). Biocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cells. Nanomedicine: Nanotechnology, Biology and Medicine. doi: https://doi.org/10.1016/j.nano.2017.07.012

Marshall, Ross J., Kalinovskyy, Yaroslav, Griffin, Sarah L., Wilson, Claire, Blight, Barry A., & Forgan, Ross S. (2017). Functional Versatility of a Series of Zr Metal–Organic Frameworks Probed by Solid-State Photoluminescence Spectroscopy. Journal of the American Chemical Society, 139(17), 6253-6260. doi: 10.1021/jacs.7b02184

Mendez Torrecillas, Carlota, Halbert, Gavin W., & Lamprou, Dimitrios A. (2017). A novel methodology to study polymodal particle size distributions produced during continuous wet granulation. International Journal of Pharmaceutics, 519(1–2), 230-239. doi: http://dx.doi.org/10.1016/j.ijpharm.2017.01.023

Michalchuk, Adam A. L., Tumanov, Ivan A., Konar, Sumit, Kimber, Simon A. J., Pulham, Colin R., & Boldyreva, Elena V. Challenges of Mechanochemistry: Is In Situ Real-Time Quantitative Phase Analysis Always Reliable? A Case Study of Organic Salt Formation. Advanced Science, 1700132-n/a. doi: 10.1002/advs.201700132

Nasr, Moheb M., Krumme, Markus, Matsuda, Yoshihiro, Trout, Bernhardt L., Badman, Clive, Mascia, Salvatore, . . . Lee, Sau L. (2017). Regulatory Perspectives on Continuous Pharmaceutical Manufacturing: Moving From Theory to Practice: September 26-27, 2016, International Symposium on the Continuous Manufacturing of Pharmaceuticals. Journal of Pharmaceutical Sciences. doi: https://doi.org/10.1016/j.xphs.2017.06.015

Osorio, Juan G., Sayin, Ridade, Kalbag, Arjun V., Litster, James D., Martinez-Marcos, Laura, Lamprou, Dimitrios A., & Halbert, Gavin W. (2017). Scaling of continuous twin screw wet granulation. AIChE Journal, 63(3), 921-932. doi: 10.1002/aic.15459

S. de Moraes, Lygia, Edwards, Darren, Florence, Alastair J., Johnston, Andrea, Johnston, Blair F., Morrison, Catriona A., & Kennedy, Alan R. (2017). Aqueous Solubility of Organic Salts. Investigating Trends in a Systematic Series of 51 Crystalline Salt Forms of Methylephedrine. Crystal Growth & Design. doi: 10.1021/acs.cgd.7b00255

Saborano, Raquel, Wongpinyochit, Thidarat, Totten, John D., Johnston, Blair F., Seib, F. Philipp, & Duarte, Iola F. (2017). Metabolic Reprogramming of Macrophages Exposed to Silk, Poly(lactic-co-glycolic acid), and Silica Nanoparticles. Advanced Healthcare Materials, 1601240-n/a. doi: 10.1002/adhm.201601240

Settanni, E., Srai, J.S., Yatskovskaya, E. and Harrington, T.S. (2017). Exploring Generalisations for Sustainability Assessment in Medicine Manufacturing Networks: proceedings of the 24th International EurOMA Conference.

Settanni, Ettore, Harrington, Tomás Seosamh, & Srai, Jagjit Singh. (2017). Pharmaceutical supply chain models: A synthesis from a systems view of operations research. Operations Research Perspectives, 4(Supplement C), 74-95. doi: https://doi.org/10.1016/j.orp.2017.05.002

Simone, Elena, Klapwijk, Anneke R., Wilson, Chick C., & Nagy, Zoltan K. (2017). Investigation of the Evolution of Crystal Size and Shape during Temperature Cycling and in the Presence of a Polymeric Additive Using Combined Process Analytical Technologies. Crystal Growth & Design, 17(4), 1695-1706. doi: 10.1021/acs.cgd.6b01683

Steendam, René R. E., & ter Horst, Joop H. (2017). Continuous Total Spontaneous Resolution. Crystal Growth & Design, 17(8), 4428-4436. doi: 10.1021/acs.cgd.7b00761

Svoboda, Vaclav, MacFhionnghaile, Pól, McGinty, John, Connor, Lauren E., Oswald, Iain D. H., & Sefcik, Jan. (2017). Continuous Cocrystallization of Benzoic Acid and Isonicotinamide by Mixing-Induced Supersaturation: Exploring Opportunities between Reactive and Antisolvent Crystallization Concepts. Crystal Growth & Design, 17(4), 1902-1909. doi: 10.1021/acs.cgd.6b01866

Totten, John D., Wongpinyochit, Thidarat, & Seib, F. Philipp. (2017). Silk nanoparticles: proof of lysosomotropic anticancer drug delivery at single-cell resolution. Journal of Drug Targeting, 1-8. doi: 10.1080/1061186X.2017.1363212

Tumanov, I. A., Michalchuk, A. A. L., Politov, A. A., Boldyreva, E. V., & Boldyrev, V. V. (2017). Inadvertent liquid assisted grinding: a key to "dry" organic mechano-co-crystallisation? CrystEngComm. doi: 10.1039/C7CE00517B

Xiouras, Christos, Ter Horst, Joop H., Van Gerven, Tom, & Stefanidis, Georgios D. (2017). Coupling Viedma Ripening with Racemic Crystal Transformations: Mechanism of Deracemization. Crystal Growth & Design, 17(9), 4965-4976. doi: 10.1021/acs.cgd.7b00908

 


 

 

2016

Adelakun, Juliet A.; Ni, Xiong-Wei. (2016). On the Kinetics of Palm Oil Crystallisation. International Journal of Engineering Research & Science, 2(10), 1. link

Agimelen, Okpeafoh S., Jawor-Baczynska, Anna, McGinty, John, Dziewierz, Jerzy, Tachtatzis, Christos, Cleary, Alison, . . . Mulholland, Anthony J. (2016). Integration of in situ imaging and chord length distribution measurements for estimation of particle size and shape. Chemical Engineering Science, 144, 87-100. doi: http://dx.doi.org/10.1016/j.ces.2016.01.007

Agnew, Lauren R., Cruickshank, Dyanne L., McGlone, Thomas, & Wilson, Chick C. (2016). Controlled production of the elusive metastable form II of acetaminophen (paracetamol): a fully scalable templating approach in a cooling environment. Chemical Communications. doi: 10.1039/C6CC01032F

Bhardwaj, Rajni M, Yang, Huaiyu, & Florence, Alastair J. (2016). Crystal structure of the co-crystal butylparaben–isonicotinamide (1/1). Acta Crystallographica Section E: Crystallographic Communications, 72(1), 53-55. doi: 10.1107/S2056989015023518

Evora, Antonio O. L., Castro, Ricardo A. E., Maria, Teresa M. R., Silva, M. Ramos, ter Horst, J. H., Canotilho, Joao, & Eusebio, M. Ermelinda S. (2016). Co-crystals of diflunisal and isomeric pyridinecarboxamides - a thermodynamics and crystal engineering contribution. CrystEngComm. doi: 10.1039/C6CE00380J

Grothe, E., Meekes, H., Vlieg, E., ter Horst, J. H., & de Gelder, R. (2016). Solvates, Salts, and Cocrystals: A Proposal for a Feasible Classification System. Crystal Growth & Design. doi: 10.1021/acs.cgd.6b00200

Harrington, T. S., & Srai, J. S. . (2016). Understanding stages of supply network emergence in technology commercialisation. International Journal of Manufacturing Technology and Management. doi: 10.1504/IJMTM.2016.10000001

Harrington, Tomás S., Phillips, Mark A., & Srai, Jagjit Singh. (2016). Reconfiguring global pharmaceutical value networks through targeted technology interventions. International Journal of Production Research, 1-17. doi: 10.1080/00207543.2016.1221541

Javid, Nadeem, Kendall, Thomas, Burns, Iain S., & Sefcik, Jan. (2016). Filtration Suppresses Laser-Induced Nucleation of Glycine in Aqueous Solutions. Crystal Growth & Design, 16(8), 4196-4202. doi: 10.1021/acs.cgd.6b00046

Klapwijk, Anneke R., Simone, Elena, Nagy, Zoltan K., & Wilson, Chick C. (2016). Tuning crystal morphology of succinic acid using a polymer additive. Crystal Growth & Design. doi: 10.1021/acs.cgd.6b00465

Marshall, Ross J., Hobday, Claire L., Murphie, Colin F., Griffin, Sarah L., Morrison, Carole A., Moggach, Stephen A., & Forgan, Ross S. (2016). Amino acids as highly efficient modulators for single crystals of zirconium and hafnium metal-organic frameworks. Journal of Materials Chemistry A, 4(18), 6955-6963. doi: 10.1039/C5TA10401G

Martinez-Marcos, Laura, Lamprou, Dimitrios A., McBurney, Roy T., & Halbert, Gavin W. (2016). A novel hot-melt extrusion formulation of albendazole for increasing dissolution properties. International Journal of Pharmaceutics, 499(1–2), 175-185. doi: http://dx.doi.org/10.1016/j.ijpharm.2016.01.006

McLachlan, Hannah, & Ni, Xiong-Wei. (2016). On the effect of added impurity on crystal purity of urea in an oscillatory baffled crystallizer and a stirred tank crystallizer. Journal of Crystal Growth, 442, 81-88. doi: http://dx.doi.org/10.1016/j.jcrysgro.2016.03.001

Ni, Xiong-Wei, & McLachlan, Hannah. (2016). An Investigation into Parameters Affecting Crystal Purity of Urea in a Stirred Tank and an Oscillatory Baffled Crystallizer. Chemical Engineering Communications, null-null. doi: 10.1080/00986445.2016.1154851

Powell, K. A., Croker, Rielly, C. D., & Nagy, Z. K. (2016). PAT-based design of agrochemical co-crystallization processes: A case-study for the selective crystallization of 1:1 and 3:2 co-crystals of p-Toluenesulfonamide/triphenylphosphine oxide. Chemical Engineering Science. doi: http://dx.doi.org/10.1016/j.ces.2016.06.005

Powell, Keddon A., Saleemi, Ali N., Rielly, Chris D., & Nagy, Zoltan K. (2016). Monitoring Continuous Crystallization of Paracetamol in the Presence of an Additive Using an Integrated PAT Array and Multivariate Methods. Organic Process Research & Development. doi: 10.1021/acs.oprd.5b00373

Ross, S. A., Lamprou, D. A., & Douroumis, D. (2016). Engineering and manufacturing of pharmaceutical co-crystals: a review of solvent-free manufacturing technologies. Chemical Communications. doi: 10.1039/C6CC01289B

Srai, Jagjit Singh, Mukesh Kumar, Gary Graham, Wendy Phillips, James Tooze, Simon Ford, Paul Beecher, Baldev Raj, Mike Gregory, Manoj Kumar Tiwari, B. Ravi, Andy Neely, Ravi Shankar, Fiona Charnley & Ashutosh Tiwari. (2016). Distributed Manufacturing: scope, challenges and opportunities. Int. J. Production Research, 54(23), 6917-6935. Link

Srirambhatla, Vijay K., Guo, Rui, Price, Sarah L., & Florence, Alastair J. (2016). Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs. Chemical Communications. doi: 10.1039/C6CC01710J

Ward, Martin R., Mackenzie, Alasdair M., & Alexander, Andrew J. (2016). Role of Impurity Nanoparticles in Laser-Induced Nucleation of Ammonium Chloride. Crystal Growth & Design. doi: 10.1021/acs.cgd.6b00882

 Wongpinyochit, T., Johnston, B. F., Seib, F. P. (2016). Manufacture and Drug Delivery Applications of Silk Nanoparticles. J. Vis. Exp., 116. doi: 10.3791/54669

Yang, Huaiyu, Yu, Xi, Raval, Vishal, Makkawi, Yassir, & Florence, Alastair. (2016). Effect of Oscillatory Flow on Nucleation Kinetics of Butyl Paraben. Crystal Growth & Design, 16(2), 875-886. doi: 10.1021/acs.cgd.5b01437

 

2015

Agimelen, Okpeafoh S., Hamilton, Peter, Haley, Ian, Nordon, Alison, Vasile, Massimiliano, Sefcik, Jan, & Mulholland, Anthony J. (2015). Estimation of particle size distribution and aspect ratio of non-spherical particles from chord length distribution. Chemical Engineering Science, 123, 629-640. doi: http://dx.doi.org/10.1016/j.ces.2014.11.014

Bhardwaj, Rajni Miglani, Johnston, Andrea, Johnston, Blair, & Florence, Alastair James. (2015). A Random Forest Model for Predicting the Crystallisability of Organic Molecules. CrystEngComm. doi: 10.1039/c4ce02403f

Bhardwaj, Rajni M, Raval, Vishal, Oswald, Iain DH, & Florence, Alastair J. (2015). Crystal structure of a mixed solvated form of amoxapine acetate. Acta Crystallographica Section E: Crystallographic Communications, 71(2), 139-141. doi: 10.1107/S2056989014028096

Brandel, Clement, & ter Horst, Joop H. (2015). Measuring induction times and crystal nucleation rates. Faraday Discussions, 179(0), 199-214. doi: 10.1039/C4FD00230J

Briggs, Naomi E. B., Schacht, Ulrich, Raval, Vishal, McGlone, Thomas, Sefcik, Jan, & Florence, Alastair J. (2015). Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer. Organic Process Research & Development, 19(12), 1903-1911. doi: 10.1021/acs.oprd.5b00206

Daly, Ronan, Harrington, Tomás S., Martin, Graham D., & Hutchings, Ian M. (2015). Inkjet printing for pharmaceutics – A review of research and manufacturing. International Journal of Pharmaceutics(0). doi: http://dx.doi.org/10.1016/j.ijpharm.2015.03.017

Hendon, Christopher H., Wittering, Kate E., Chen, Teng-Hao, Kaveevivitchai, Watchareeya, Popov, Ilya, Butler, Keith T., . . . Walsh, Aron. (2015). Absorbate-Induced Piezochromism in a Porous Molecular Crystal. Nano Letters, 15(3), 2149-2154. doi: 10.1021/acs.nanolett.5b00144

Hunter, Steven, Coster, Paul L., Davidson, Alistair J., Millar, David I. A., Parker, Stewart F., Marshall, William G., . . . Pulham, Colin R. (2015). High-Pressure Experimental and DFT-D Structural Studies of the Energetic Material FOX-7. The Journal of Physical Chemistry C, 119(5), 2322-2334. doi: 10.1021/jp5110888

McGlone, Thomas, Briggs, Naomi, Clark, Catriona, Brown, Cameron, Sefcik, Jan, & Florence, Alastair J. (2015). Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization. Organic Process Research & Development. doi: 10.1021/acs.oprd.5b00225

Powell, K. A., Saleemi, A. N., Rielly, C. D., & Nagy, Z. K. (2015). Periodic steady-state flow crystallization of a pharmaceutical drug using MSMPR operation. Chemical Engineering and Processing: Process Intensification(0). doi: http://dx.doi.org/10.1016/j.cep.2015.01.002

Powell, Keddon A., Bartolini, Giulia, Wittering, Kate E., Saleemi, Ali N., Wilson, Chick C., Rielly, Chris D., & Nagy, Zoltan K. (2015). Toward Continuous Crystallization of Urea-Barbituric Acid: A Polymorphic Co-Crystal System. Crystal Growth & Design, 15(10), 4821-4836. doi: 10.1021/acs.cgd.5b00599

Price, Sarah, Rimez, Bart, Sun, Wenhao, Peters, Baron, Christenson, Hugo, Hughes, Colan, . . . Wu, David T. (2015). Nucleation in complex multi-component and multi-phase systems: general discussion. Faraday Discussions, 179(0), 503-542. doi: 10.1039/C5FD90039E

Reus, Marloes A., van der Heijden, Antoine E. D. M., & ter Horst, Joop H. (2015). Solubility Determination from Clear Points upon Solvent Addition. Organic Process Research & Development. doi: 10.1021/acs.oprd.5b00156

Ross, Steven, Scoutaris, Nicolaos, Lamprou, Dimitrios, Mallinson, David, & Douroumis, Dennis. (2015). Inkjet printing of insulin microneedles for transdermal delivery. Drug Delivery and Translational Research, 5(4), 451-461. doi: 10.1007/s13346-015-0251-1

Sans, Victor, Porwol, Luzian, Dragone, Vincenza, & Cronin, Leroy. (2015). A self optimizing synthetic organic reactor system using real-time in-line NMR spectroscopy. Chemical Science, 6(2), 1258-1264. doi: 10.1039/C4SC03075C

Sayin, R., Martinez-Marcos, L., Osorio, J. G., Cruise, P., Jones, I., Halbert, G. W., . . . Litster, J. D. (2015). Investigation of an 11mm diameter twin screw granulator: Screw element performance and in-line monitoring via image analysis. Int J Pharm. doi: 10.1016/j.ijpharm.2015.09.024

Siddique, Humera, Brown, Cameron J., Houson, Ian, & Florence, Alastair J. (2015). Establishment of a Continuous Sonocrystallization Process for Lactose in an Oscillatory Baffled Crystallizer. Organic Process Research & Development, 19(12), 1871-1881. doi: 10.1021/acs.oprd.5b00127

Srai, Jagjit Singh, Harrington, Tomás, Alinaghian, Leila, & Phillips, Mark. (2015). Evaluating the potential for the continuous processing of pharmaceutical products—a supply network perspective. Chemical Engineering and Processing: Process Intensification, 97, 248-258. doi: http://dx.doi.org/10.1016/j.cep.2015.07.018

Su, Qinglin, Benyahia, Brahim, Nagy, Zoltan K., & Rielly, Chris D. (2015). Mathematical Modeling, Design, and Optimization of a Multisegment Multiaddition Plug-Flow Crystallizer for Antisolvent Crystallizations. Organic Process Research & Development, 19(12), 1859-1870. doi: 10.1021/acs.oprd.5b00110

Su, Qinglin, Nagy, Zoltan K., & Rielly, Chris D. (2015). Pharmaceutical crystallisation processes from batch to continuous operation using MSMPR stages: Modelling, design, and control. Chemical Engineering and Processing: Process Intensification, 89(0), 41-53. doi: http://dx.doi.org/10.1016/j.cep.2015.01.001

Sun, Changquan Calvin, Sun, Wenhao, Price, Sarah, Hughes, Colan, Ter Horst, Joop, Veesler, Stephane, . . . Salvalaglio, Matteo. (2015). Solvent and additive interactions as determinants in the nucleation pathway: general discussion. Faraday Discussions, 179(0), 383-420. doi: 10.1039/C5FD90038G

Sun, Wenhao, Booth, Samuel, Myerson, Allan, Hughes, Colan, Pan, Haihua, Coquerel, Gerard, . . . Sommerdijk, Nico. (2015). Time and space resolved methods: general discussion. Faraday Discussions, 179(0), 247-267. doi: 10.1039/C5FD90037A

Tachtatzis, Christos, Sheridan, Rachel, Michie, Craig, Atkinson, Robert C, Cleary, Alison, Dziewierz, Jerzy, . . . Sefcik, Jan. (2015). Image-based monitoring for early detection of fouling in crystallisation processes. Chemical Engineering Science. doi: 10.1016/j.ces.2015.01.038

Ward, Martin R., Jamieson, William, Leckey, Claire, & Alexander, Andrew. (2015). Laser-induced nucleation of carbon dioxide bubbles. The Journal of Chemical Physics, 142(144501). doi: 10.1063/1.4917022

Ward, Martin R., Rae, Alasdair, & Alexander, Andrew J. (2015). Nonphotochemical Laser-Induced Crystal Nucleation by an Evanescent Wave. Crystal Growth & Design, 15(9), 4600-4605. doi: 10.1021/acs.cgd.5b00854

Wittering, K. E., Agnew, L. R., Klapwijk, A. R., Robertson, K., Cousen, A. J. P., Cruickshank, D. L., & Wilson, C. C. (2015). Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives. CrystEngComm, 17(19), 3610-3618. doi: 10.1039/C5CE00297D

Wongpinyochit, Thidarat, Uhlmann, Petra, Urquhart, Andrew J., & Seib, F. Philipp. (2015). PEGylated Silk Nanoparticles for Anticancer Drug Delivery. Biomacromolecules, 16(11), 3712-3722. doi: 10.1021/acs.biomac.5b01003

Xiouras, Christos, Van Aeken, Jasper, Panis, Joris, Ter Horst, Joop H., Van Gerven, Tom, & Stefanidis, Georgios D. (2015). Attrition-Enhanced Deracemization of NaClO3: Comparison between Ultrasonic and Abrasive Grinding. Crystal Growth & Design, 15(11), 5476-5484. doi: 10.1021/acs.cgd.5b01108

Yang, Huaiyu. (2015). Relation between metastable zone width and induction time of butyl paraben in ethanol. CrystEngComm, 17, 577-586. doi: 10.1039/C4CE01625D

 

2014

Arlin, Jean-Baptiste, Bhardwaj, Rajni M, Johnston, Andrea, Miller, Gary J, Bardin, Julie, MacDougall, Fiona, . . . Florence, Alastair J. (2014). Structure and stability of two polymorphs of creatine and its monohydrate. CrystEngComm, 16(35), 8197-8204. DOI: 10.1039/C4CE00508B

Brown, C. J., Lee, Y. C., Nagy, Z. K., & Ni, X. (2014). Evaluation of crystallization kinetics of adipic acid in an oscillatory baffled crystallizer. CrystEngComm, 16(34), 8008. doi: 10.1039/c4ce00192c

Callahan, Craig J., & Ni, Xiong-Wei. (2014). An investigation into the effect of mixing on the secondary nucleation of sodium chlorate in a stirred tank and an oscillatory baffled crystallizer. CrystEngComm, 16(4), 690. doi: 10.1039/c3ce41467a

Delori, Amit, Maclure, Pauline, Bhardwaj, Rajni M, Johnston, Andrea, Florence, Alastair J, Sutcliffe, Oliver B, & Oswald, Iain DH. (2014). Drug solid solutions–a method for tuning phase transformations. CrystEngComm, 16(26), 5827-5831. DOI: 10.1039/C4CE00211C

Etherson, K.; Halbert G.; Elliott, M.: Determination of Excipient Based Solubility Increases using the CheqSol Method. Int J Pharm, 2014, 465(1-2): 202-209. DOI: 10.1016/j.ijpharm.2014.02.007.

Jawor-Baczynska, A. (2014). "Development of continuous crystallisation processes of pharmaceutical compounds to achieve better control over particle attributes". 45th BACG conference, Leeds, UK, 13-15 July 2014.

McKellar, Scott C., Kennedy, Alan R., McCloy, Neil C., McBride, Eileen, & Florence, Alastair J. (2014). Formulation of Liquid Propofol as a Cocrystalline Solid. Crystal Growth & Design, 14(5), 2422-2430. doi: 10.1021/cg500155p

Pulham, Colin R. (2014). Editorial. CrystEngComm, 16(26), 5752-5752. doi: 10.1039/C4CE90086C

Sans, Victor, Glatzel, Stefan, Douglas, Fraser J., Maclaren, Donald A., Lapkin, Alexei, & Cronin, Leroy. (2014). Non-equilibrium dynamic control of gold nanoparticle and hyper-branched nanogold assemblies. Chemical Science, 5(3), 1153. doi: 10.1039/c3sc53223b

Srai, J.S.; Harrington, T.S.; Alinaghian, L.: An Approach to Exploring Integration Benefits of Continuous Flow Technologies within Pharmaceutical Supply Chains. Chemistry Today, 2014, Vol. 32, No.4, pp.14-19. link

Thomas, Lynne H., Klapwijk, Anneke R., Wales, Craig, & Wilson, Chick C. (2014). Intermolecular hydrogen transfer and solubility tuning in multi-component molecular crystals of the API piroxicam. CrystEngComm, 16(26), 5924. doi: 10.1039/c4ce00246f

Wittering, Kate, King, Josh, Thomas, Lynne, & Wilson, Chick. (2014). From Evaporative to Cooling Crystallisation: An Initial Co-Crystallisation Study of Cytosine and Its Fluorinated Derivative with 4- chloro-3,5-dinitrobenzoic Acid. Crystals, 4(2), 123-140. doi: 10.3390/cryst4020123

Yang, Huaiyu, Chen, Hong, & Rasmuson, Åke C. (2014). Sandwich crystals of butyl paraben. CrystEngComm, 16(37), 8863. doi: 10.1039/c4ce01320d

Yang, Huaiyu, & Rasmuson, Åke C. (2014). Ternary phase diagrams of ethyl paraben and propyl paraben in ethanol aqueous solvents. Fluid Phase Equilibria, 376, 69-75. doi: 10.1016/j.fluid.2014.05.036

Zhao, Lihua, Raval, Vishal, Briggs, Naomi E. B., Bhardwaj, Rajni M., McGlone, Thomas, Oswald, Iain D. H., & Florence, Alastair J. (2014). From discovery to scale-up: α-lipoic acid : nicotinamide co-crystals in a continuous oscillatory baffled crystalliser. CrystEngComm, 16(26), 5769. doi: 10.1039/c4ce00154k

 

2013

Bhardwaj, Rajni M, Johnston, Blair F, Oswald, Iain DH, & Florence, Alastair J. (2013). A complementary experimental and computational study of loxapine succinate and its monohydrate. Acta Crystallographica Section C: Crystal Structure Communications, 69(11), 1273-1278. DOI: 10.1107/S0108270113029363

Bhardwaj, Rajni M, Price, Louise S, Price, Sarah L, Reutzel-Edens, Susan M, Miller, Gary J, Oswald, Iain DH, . . . Florence, Alastair J. (2013). Exploring the experimental and computed crystal energy landscape of olanzapine. Crystal Growth & Design, 13(4), 1602-1617. DOI: 10.1021/cg301826s

Braun, Doris E, Bhardwaj, Rajni M, Arlin, Jean-Baptiste, Florence, Alastair J, Kahlenberg, Volker, Griesser, Ulrich J, . . . Price, Sarah L. (2013). Absorbing a Little Water: The Structural, Thermodynamic, and Kinetic Relationship between Pyrogallol and Its Tetarto-Hydrate. Crystal Growth & Design, 13(9), 4071-4083. DOI: 10.1021/cg4009015

Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J., & Cronin, L. (2013). 3D-printed devices for continuous-flow organic chemistry. Beilstein J Org Chem, 9, 951-959. doi: 10.3762/bjoc.9.109

Jawor-Baczynska, Anna, Moore, Barry D., Lee, Han Seung, McCormick, Alon V., & Sefcik, Jan. (2013). Population and size distribution of solute-rich mesospecies within mesostructured aqueous amino acid solutions. Faraday Discussions, 167, 425. doi: 10.1039/c3fd00066d

Jawor-Baczynska, Anna, Sefcik, Jan, & Moore, Barry D. (2013). 250 nm Glycine-Rich Nanodroplets Are Formed on Dissolution of Glycine Crystals But Are Too Small To Provide Productive Nucleation Sites. Crystal Growth & Design, 13(2), 470-478. doi: 10.1021/cg300150u

Kitson, Philip J., Symes, Mark D., Dragone, Vincenza, & Cronin, Leroy. (2013). Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification. Chemical Science, 4(8), 3099. doi: 10.1039/c3sc51253c

Manninen, Mikko, Gorshkova, Elena, Immonen, Kirsi, & Ni, Xiong-Wei. (2013). Evaluation of axial dispersion and mixing performance in oscillatory baffled reactors using CFD. Journal of Chemical Technology & Biotechnology, 88(4), 553-562. doi: 10.1002/jctb.3979

Srai, Jagjit Singh, & Alinaghian, Leila Sadat. (2013). Value Chain Reconfiguration in Highly Disaggregated Industrial Systems: Examining the Emergence of Health Care Diagnostics. Global Strategy Journal, 3(1), 88-108. doi: 10.1111/j.2042-5805.2012.01047.x

Ward, Martin R., Botchway, Stanley W., Ward, Andrew D., & Alexander, Andrew J. (2013). Second-harmonic scattering in aqueous urea solutions: evidence for solute clusters? Faraday Discussions, 167(0), 441-454. doi: 10.1039/C3FD00089C

Yang, Huaiyu, & Rasmuson, Åke C. (2013). Nucleation of Butyl Paraben in Different Solvents. Crystal Growth & Design, 13(10), 4226-4238. doi: 10.1021/cg400177u

 

2012

Braun, Doris E, Bhardwaj, Rajni M, Florence, Alastair J, Tocher, Derek A, & Price, Sarah L. (2012). Complex Polymorphic System of Gallic Acid Five Monohydrates, Three Anhydrates, and over 20 Solvates. Crystal Growth & Design, 13(1), 19-23. Doi: 10.1021/cg301506x

Brown, Cameron J., & Ni, Xiong-Wei. (2012). Determination of metastable zone width, mean particle size and detectable number density using video imaging in an oscillatory baffled crystallizer. CrystEngComm, 14(8), 2944. doi: 10.1039/c2ce06628a

Callahan, Craig J., & Ni, Xiong-Wei. (2012). Probing into Nucleation Mechanisms of Cooling Crystallization of Sodium Chlorate in a Stirred Tank Crystallizer and an Oscillatory Baffled Crystallizer. Crystal Growth & Design, 12(5), 2525-2532. doi: 10.1021/cg300135w

de la Oliva, A. R., Sans, V., Miras, H. N., Yan, J., Zang, H., Richmond, C. J., . . . Cronin, L. (2012). Assembly of a gigantic polyoxometalate cluster {W200Co8O660} in a networked reactor system. Angew Chem Int Ed Engl, 51(51), 12759-12762. doi: 10.1002/anie.201206572

Harrington, T.S., Kirkwood, D.A., Srai, J.S., 2012. Performance Metric Selection Methodology for Multi- Organizational Service Network Integration. The Journal of Applied Management and Entrepreneurship 17 (3), 20–35.5. link

Kitson, P. J., Rosnes, M. H., Sans, V., Dragone, V., & Cronin, L. (2012). Configurable 3D-Printed millifluidic and microfluidic 'lab on a chip' reactionware devices. Lab Chip, 12(18), 3267-3271. doi: 10.1039/c2lc40761b

McKellar, Scott C, Urquhart, Andrew J, Lamprou, Dimitrios A, & Florence, Alastair J. (2012). Polymer templating of supercooled indomethacin for polymorph selection. ACS combinatorial science, 14(3), 155-159. DOI: 10.1021/co200175e

Richmond, C. J., Miras, H. N., de la Oliva, A. R., Zang, H., Sans, V., Paramonov, L., . . . Cronin, L. (2012). A flow-system array for the discovery and scale up of inorganic clusters. Nat Chem, 4(12), 1037-1043. doi: 10.1038/nchem.1489

Saleemi, A. N., Rielly, C. D., & Nagy, Z. K. (2012). Monitoring of the combined cooling and antisolvent crystallisation of mixtures of aminobenzoic acid isomers using ATR-UV/vis spectroscopy and FBRM. Chemical Engineering Science, 77, 122-129. doi: http://dx.doi.org/10.1016/j.ces.2012.02.005

Saleemi, Ali N., Rielly, Chris D., & Nagy, Zoltan K. (2012). Comparative Investigation of Supersaturation and Automated Direct Nucleation Control of Crystal Size Distributions using ATR-UV/vis Spectroscopy and FBRM. Crystal Growth & Design, 12(4), 1792-1807. doi: 10.1021/cg201269c

Srai, Tomás Seosamh Harrington; Jagjit Singh. (2012). Defining product-service network configurations and location roles: a current and future state analysis framework for international engineering operations. International Journal of Product Development (IJPD), 17(3/4), 228-253. doi: 10.1504/IJPD.2012.052103

Sypek, Katarzyna, Burns, Iain S, Florence, Alastair J, & Sefcik, Jan. (2012). In Situ Monitoring of Stirring Effects on Polymorphic Transformations during Cooling Crystallization of Carbamazepine. Crystal Growth & Design, 12(10), 4821-4828. DOI: 10.1021/cg3005689

 

2011

Brown, C. J.; Ni, X.-W., Evaluation of Growth Kinetics of Antisolvent Crystallization of Paracetamol in an Oscillatory Baffled Crystallizer Utilizing Video Imaging. Crystal Growth & Design 2011, 11 (9), 3994-4000. doi: 10.1021/cg200560b

Brown, Cameron J., & Ni, Xiongwei. (2011). Online Evaluation of Paracetamol Antisolvent Crystallization Growth Rate with Video Imaging in an Oscillatory Baffled Crystallizer. Crystal Growth & Design, 11(3), 719-725. doi:

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